Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.47 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.47 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.47 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.47 |
| ▸ | GRIK5 | Q16478 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | CA12 | O43570 | 6/20 | 0.39 |
| ▸ | CA9 | Q16790 | 6/20 | 0.39 |
| ▸ | CA1 | P00915 | 5/20 | 0.39 |
| ▸ | CA2 | P00918 | 5/20 | 0.39 |
| ▸ | TSHR | P16473 | 5/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | TP53 | P04637 | 2/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26035300 | 0.90 | LMNA (0.50) | LMNAKDM4ECYP1A2GRIA1GRIA2 | |
| SCHEMBL10508539 | 0.89 | LMNA (0.53) | LMNAKDM4ECYP1A2GRIA1GRIA2 | |
| SCHEMBL24322118 | 0.83 | TYMP (0.54) | LMNATYMPHPGD | |
| SCHEMBL28652297 | 0.79 | LMNA (0.67) | LMNAKDM4ECYP1A2GRIA1GRIA2 | |
| SCHEMBL26035304 | 0.79 | TSHR (0.44) | LMNAKDM4ECYP1A2GRIA1GRIA2 | |
| SCHEMBL24205068 | 0.77 | TSHR (0.45) | LMNAKDM4ECYP1A2GRIA1GRIA2 | |
| SCHEMBL28820753 | 0.77 | LMNA (0.71) | LMNAKDM4ECYP1A2GRIA1GRIA2 | |
| SCHEMBL11228302 | 0.75 | L3MBTL1 (0.50) | LMNATSHRALDH1A1TP53HIF1A | |
| SCHEMBL18561654 | 0.75 | LMNA (0.50) | LMNAKDM4ECYP1A2GRIA1GRIA2 | |
| SCHEMBL11252365 | 0.74 | LMNA (0.56) | LMNAKDM4ECYP1A2GRIA1GRIA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0898590-A1 | BIODEGRADABLE POLYMERS GRAFTED WITH AMINO ACIDS | CORNELL RESEARCH FOUNDATION, INC. (US) | 1999-03-03 | — | — | EP | disclosed |
| WO-1997042249-A1 | BIODEGRADABLE POLYMERS GRAFTED WITH AMINO ACIDS | CORNELL RESEARCH FOUNDATION, INC. (US) | 1997-11-13 | — | — | WO | disclosed |
| US-5610241-A | Reactive graft polymer with biodegradable polymer backbone and method for preparing reactive biodegradable polymers | CORNELL RESEARCH FOUNDATION, INC. (US) | 1997-03-11 | — | — | US | disclosed |