Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | RET | P07949 | 1/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
| ▸ | XBP1 | P17861 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | BLM | P54132 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | IDO1 | P14902 | 1/20 | 0.37 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.37 |
| ▸ | ACP3 | P15309 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30816126 | 0.80 | ALDH1A1 (0.44) | RAB9AALDH1A1KMT2ALMNATSHR | |
| SCHEMBL5189353 | 0.78 | HTR2A (0.37) | RAB9ALMNAHTR2ASMN1; SMN2 | |
| SCHEMBL660714 | 0.75 | HTR2A (0.43) | RAB9AALDH1A1KMT2ALMNATSHR | |
| SCHEMBL7343966 | 0.75 | ALDH1A1 (0.44) | RAB9AALDH1A1KMT2ALMNATSHR | |
| SCHEMBL30388241 | 0.75 | ALDH1A1 (0.41) | RAB9AALDH1A1KMT2ALMNATSHR | |
| SCHEMBL23921624 | 0.75 | HTR2A (0.43) | RAB9AALDH1A1KMT2ALMNATSHR | |
| SCHEMBL9810549 | 0.75 | ALDH1A1 (0.41) | RAB9AALDH1A1KMT2ALMNATSHR | |
| SCHEMBL25180650 | 0.75 | ALDH1A1 (0.41) | RAB9AALDH1A1KMT2ALMNATSHR | |
| SCHEMBL660713 | 0.75 | ALDH1A1 (0.44) | RAB9AALDH1A1KMT2ALMNATSHR | |
| SCHEMBL7397055 | 0.75 | RAB9A (0.44) | RAB9AALDH1A1KMT2ALMNATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090076124-A1 | DEUTERIUM-ENRICHED ROPINIROLE | PROTIA, LLC (US) | 2009-03-19 | — | — | US | disclosed |
| US-20090076124-A1 | DEUTERIUM-ENRICHED ROPINIROLE | PROTIA, LLC (US) | 2009-03-19 | — | — | US | disclosed |
| EP-0836599-A1 | 1,6-DISUBSTITUTED ISOCHROMANS FOR TREATMENT OF MIGRAINE HEADACHES | PHARMACIA & UPJOHN COMPANY (US) | 1998-04-22 | — | — | EP | disclosed |
| WO-1997002259-A1 | 1,6-DISUBSTITUTED ISOCHROMANS FOR TREATMENT OF MIGRAINE HEADACHES | PHARMACIA & UPJOHN COMPANY (US) | 1997-01-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090076124-A1 | DEUTERIUM-ENRICHED ROPINIROLE | DRD1, DRD3, DRD4 | RAB9A 937/4885ALDH1A1 2582/4885KMT2A 1999/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.