Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 9/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.37 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.37 |
| ▸ | ITGA2 | P17301 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8548741 | 0.85 | POLB (0.41) | FFAR1MEN1KMT2AALDH1A1HPGD | |
| Hydrochloric Acid SCHEMBL8592836 | 0.85 | POLB (0.44) | FFAR1KMT2AALDH1A1POLB | |
| Hydrochloric Acid SCHEMBL8593976 | 0.82 | POLB (0.38) | FFAR1KMT2AALDH1A1POLB | |
| Bromide SCHEMBL8551319 | 0.78 | POLB (0.44) | MEN1KMT2AALDH1A1HPGDPOLB | |
| Bromide SCHEMBL8553025 | 0.76 | MAPT (0.49) | MEN1KMT2AALDH1A1HPGDPOLB | |
| Hydrochloric Acid SCHEMBL8551971 | 0.76 | CYP2C9 (0.51) | MEN1KMT2AALDH1A1POLBL3MBTL1 | |
| Bromide SCHEMBL8553387 | 0.75 | POLB (0.50) | MEN1KMT2AALDH1A1HPGDPOLB | |
| SCHEMBL9409455 | 0.73 | HDAC3 (0.50) | — | |
| SCHEMBL8554053 | 0.70 | MAPT (0.51) | MEN1KMT2AALDH1A1POLBL3MBTL1 | |
| Hydrochloric Acid SCHEMBL8549386 | 0.70 | POLB (0.48) | KMT2AALDH1A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0858457-A1 | 5-MEMBERED HETEROCYCLES, PHARMACEUTICAL AGENTS CONTAINING SAID COMPOUNDS AND THE USE THEREOF AND METHODS OF PRODUCING THEM | Dr. Karl Thomae GmbH (DE) | 1998-08-19 | — | — | EP | disclosed |
| WO-1997015567-A1 | 5-MEMBERED HETEROCYCLES, PHARMACEUTICAL AGENTS CONTAINING SAID COMPOUNDS AND THE USE THEREOF AND METHODS OF PRODUCING THEM | DR. KARL THOMAE GMBH (DE) | 1997-05-01 | — | — | WO | disclosed |