Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.49 |
| ▸ | MEN1 | O00255 | 3/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | RAB9A | P51151 | 5/20 | 0.44 |
| ▸ | NPC1 | O15118 | 4/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8592052 | 0.99 | MAPT (0.50) | MAPTKDM4EKMT2AMEN1ALDH1A1 | |
| Bromide SCHEMBL8554224 | 0.99 | MAPT (0.50) | MAPTKDM4EKMT2AMEN1ALDH1A1 | |
| Bromide SCHEMBL8553025 | 0.90 | MAPT (0.49) | MAPTKDM4EKMT2AMEN1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL8593690 | 0.86 | CXCR1 (0.44) | MAPTKDM4EKMT2AMEN1ALDH1A1 | |
| Bromide SCHEMBL8554391 | 0.85 | LMNA (0.48) | MAPTKDM4EKMT2AMEN1ALDH1A1 | |
| SCHEMBL8550534 | 0.83 | KMT2A (0.44) | MAPTKMT2AMEN1ALDH1A1SMN1; SMN2 | |
| Bromide SCHEMBL8553387 | 0.79 | POLB (0.50) | MAPTKDM4EKMT2AMEN1ALDH1A1 | |
| Bromide SCHEMBL8554165 | 0.79 | KMT2A (0.42) | MAPTKDM4EKMT2AMEN1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL9409427 | 0.74 | MEN1 (0.53) | KMT2AMEN1ALDH1A1RAB9ANPC1 | |
| SCHEMBL6875704 | 0.73 | MAPT (0.65) | MAPTKDM4EKMT2AMEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0858457-A1 | 5-MEMBERED HETEROCYCLES, PHARMACEUTICAL AGENTS CONTAINING SAID COMPOUNDS AND THE USE THEREOF AND METHODS OF PRODUCING THEM | Dr. Karl Thomae GmbH (DE) | 1998-08-19 | — | — | EP | claimed |
| WO-1997015567-A1 | 5-MEMBERED HETEROCYCLES, PHARMACEUTICAL AGENTS CONTAINING SAID COMPOUNDS AND THE USE THEREOF AND METHODS OF PRODUCING THEM | DR. KARL THOMAE GMBH (DE) | 1997-05-01 | — | — | WO | claimed |