Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL38659428 | 0.78 | BRD4 (0.38) | PDCD1CD274 | |
| SCHEMBL5991452 | 0.75 | IRAK4 (0.35) | CD274 | |
| SCHEMBL31048309 | 0.74 | CREBBP (0.34) | PDCD1CD274 | |
| SCHEMBL6978438 | 0.73 | IRAK4 (0.32) | CD274 | |
| SCHEMBL8552930 | 0.73 | NOS3 (0.48) | — | |
| SCHEMBL8592596 | 0.72 | NOS2 (0.45) | — | |
| SCHEMBL8592599 | 0.72 | NOS2 (0.45) | — | |
| SCHEMBL8554107 | 0.71 | — | — | |
| SCHEMBL31048376 | 0.71 | — | — | |
| SCHEMBL24532573 | 0.70 | MKNK1 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0824523-A1 | NITRIC OXIDE SYNTHASE INHIBITORS DERIVED FROM CYCLIC AMIDINES | G.D. Searle & Co. (US) | 1998-02-25 | — | — | EP | disclosed |
| WO-1996035677-A1 | NITRIC OXIDE SYNTHASE INHIBITORS DERIVED FROM CYCLIC AMIDINES | G.D. SEARLE & CO. (US) | 1996-11-14 | — | — | WO | disclosed |