Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD9 | Q9H8M2 | 1/20 | 0.40 |
| ▸ | NOTUM | Q6P988 | 5/20 | 0.36 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.36 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.35 |
| ▸ | MYC | P01106 | 1/20 | 0.35 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.35 |
| ▸ | CTSB | P07858 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.34 |
| ▸ | PDE5A | O76074 | 1/20 | 0.34 |
| ▸ | PDE1A | P54750 | 1/20 | 0.34 |
| ▸ | PDE1B | Q01064 | 1/20 | 0.34 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.34 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.34 |
| ▸ | PDE1C | Q14123 | 1/20 | 0.34 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.34 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8555144 | 0.83 | MAPT (0.36) | BRD9ALDH1A1L3MBTL1POLBLMNA | |
| SCHEMBL29938165 | 0.82 | NOTUM (0.38) | NOTUMKEAP1NFE2L2TDP1MYC | |
| SCHEMBL24151268 | 0.82 | NOTUM (0.38) | NOTUMKEAP1NFE2L2TDP1MYC | |
| SCHEMBL4067527 | 0.78 | NOTUM (0.36) | NOTUMKEAP1NFE2L2TDP1MYC | |
| SCHEMBL9350427 | 0.76 | NOTUM (0.40) | NOTUMTDP1MYCNR4A1CTSB | |
| SCHEMBL9706662 | 0.76 | NOTUM (0.40) | NOTUMTDP1MYCNR4A1CTSB | |
| SCHEMBL31448171 | 0.76 | ALDH1A1 (0.47) | NOTUMKEAP1NFE2L2TSHRALDH1A1 | |
| SCHEMBL9706659 | 0.75 | NOTUM (0.39) | NOTUMTDP1MYCNR4A1CTSB | |
| SCHEMBL9706512 | 0.75 | NOTUM (0.41) | NOTUMTDP1MYCNR4A1CTSB | |
| SCHEMBL9706620 | 0.74 | BRD9 (0.34) | BRD9NOTUMTDP1MYCNR4A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0863142-A1 | Heterocyclic herbicides | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1998-09-09 | — | — | EP | disclosed |