SCHEMBL9706620

SCHEMBL9706620

CCc1cc(=O)n(-c2cc(C(=O)O)c(Cl)cc2F)c(=O)n1C

nearest known ligand 0.34

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
BRD9 Q9H8M2 1/20 0.34
HPGD P15428 1/20 0.34
SMN1; SMN2 Q16637 1/20 0.34
NOTUM Q6P988 3/20 0.33
KMT2A Q03164 2/20 0.32
BAZ2B Q9UIF8 1/20 0.32
BAZ2A Q9UIF9 1/20 0.32
DRD3 P35462 1/20 0.32
MYC P01106 1/20 0.32
NR4A1 P22736 1/20 0.32
CTSB P07858 1/20 0.32
TDP1 Q9NUW8 1/20 0.32
MAPT P10636 1/20 0.31
TSHR P16473 1/20 0.31
EPHX2 P34913 1/20 0.30
MEN1 O00255 1/20 0.30
LMNA P02545 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9706711 0.91 HPGD (0.33) BRD9HPGDSMN1; SMN2NOTUMKMT2A
SCHEMBL9521004 0.85 NOTUM (0.31) BRD9HPGDSMN1; SMN2NOTUM
SCHEMBL9706612 0.85 LMNA (0.35) BRD9HPGDSMN1; SMN2BAZ2BBAZ2A
SCHEMBL9350427 0.84 NOTUM (0.40) HPGDSMN1; SMN2NOTUMKMT2AMYC
SCHEMBL9796415 0.84 BAZ2B (0.37) BRD9HPGDSMN1; SMN2KMT2ABAZ2B
SCHEMBL24151268 0.82 NOTUM (0.38) HPGDSMN1; SMN2NOTUMKMT2AMYC
SCHEMBL29938165 0.82 NOTUM (0.38) HPGDSMN1; SMN2NOTUMKMT2AMYC
SCHEMBL2976620 0.81 NOTUM (0.34) HPGDSMN1; SMN2NOTUMKMT2AMYC
SCHEMBL9796374 0.80 BAZ2B (0.34) HPGDSMN1; SMN2BAZ2BBAZ2AMAPT
SCHEMBL9522017 0.79 HPGD (0.33) HPGDSMN1; SMN2NOTUMMYCNR4A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0195346-B1 3-ARYL URACILES AND THEIR USE AS HERBICIDES CIBA-GEIGY AG (CH) 1992-06-24 EP claimed