Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | UBE2M | P61081 | 3/20 | 0.49 |
| ▸ | DCUN1D1 | Q96GG9 | 3/20 | 0.49 |
| ▸ | DRD2 | P14416 | 12/20 | 0.48 |
| ▸ | DRD3 | P35462 | 11/20 | 0.48 |
| ▸ | HTR2A | P28223 | 10/20 | 0.48 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.47 |
| ▸ | DRD4 | P21917 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8703719 | 0.91 | DRD2 (0.53) | DRD2DRD3HTR2ASLC6A4 | |
| SCHEMBL8549267 | 0.89 | DRD2 (0.46) | DRD2DRD3HTR2ASLC6A4MAPT | |
| SCHEMBL8707882 | 0.88 | DRD2 (0.54) | DRD2DRD3HTR2ASLC6A4 | |
| SCHEMBL8548622 | 0.88 | DRD2 (0.47) | DRD2DRD3HTR2ASLC6A4 | |
| SCHEMBL8550671 | 0.85 | DRD2 (0.56) | DRD2DRD3HTR2A | |
| SCHEMBL8703395 | 0.85 | DRD2 (0.61) | DRD2DRD3HTR2ASLC6A4 | |
| SCHEMBL8551620 | 0.84 | DRD2 (0.48) | DRD2DRD3HTR2ASLC6A4MAPT | |
| SCHEMBL8703762 | 0.84 | DRD2 (0.47) | DRD2DRD3HTR2ASLC6A4 | |
| SCHEMBL8548439 | 0.83 | DRD2 (0.48) | UBE2MDCUN1D1DRD2DRD3HTR2A | |
| SCHEMBL8552345 | 0.83 | DRD2 (0.54) | DRD2DRD3HTR2ASLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5792763-A | MIGRAINES; ANALGESICS; DISEASES LINKED TO DECREASED NEUROTRANMISSION OF SEROTONIN IN MAMMALS | ELI LILLY AND COMPANY (US) | 1998-08-11 | — | — | US | disclosed |
| WO-1998015545-A1 | NEW SEROTONIN 5-HT1F AGONISTS | ELI LILLY AND COMPANY (US) | 1998-04-16 | — | — | WO | disclosed |
| EP-0835869-A2 | New serotonin 5-HT1F agonists | ELI LILLY AND COMPANY (US) | 1998-04-15 | — | — | EP | disclosed |