SCHEMBL8551639

SCHEMBL8551639

NC(=O)c1ccsc1[CH]C(N)=S

nearest known ligand 0.50

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.50
MAPT P10636 4/20 0.50
KMT2A Q03164 2/20 0.50
MEN1 O00255 1/20 0.50
MAPK1 P28482 1/20 0.50
PTK2 Q05397 1/20 0.42
HSD17B10 Q99714 3/20 0.41
GAA P10253 1/20 0.41
MAPK8 P45983 9/20 0.38
MAPK10 P53779 5/20 0.38
HTT P42858 1/20 0.36
KDM4E B2RXH2 1/20 0.35
HPGD P15428 1/20 0.35
TSHR P16473 1/20 0.35
NPC1 O15118 2/20 0.35
RAB9A P51151 2/20 0.35
TP53 P04637 1/20 0.34
SMN1; SMN2 Q16637 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3252627 0.79 ALDH1A1 (0.55) ALDH1A1MAPTKMT2AMEN1MAPK1
SCHEMBL8551215 0.73 ALDH1A1 (0.48) ALDH1A1MAPTKMT2AMEN1MAPK1
SCHEMBL3645135 0.71 ALDH1A1 (0.47) ALDH1A1MAPTKMT2AMEN1MAPK1
SCHEMBL5067843 0.71
SCHEMBL17818777 0.68 MAPK10 (0.50) ALDH1A1MAPTKMT2AMEN1MAPK1
SCHEMBL161830 0.67
SCHEMBL2889862 0.67 MAPT (0.61) ALDH1A1MAPTKMT2AMEN1MAPK1
SCHEMBL9528369 0.67
SCHEMBL164691 0.67
SCHEMBL23323409 0.67 PTK2 (0.69) ALDH1A1MAPTKMT2AMEN1MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0639574-B1 2-aminothiazolecarboxamide derivatives, processes for their preparation and their use for controlling phytopathogenic organisms LUCKY LTD (KR) 1998-06-10 EP disclosed
US-5514643-A FUNGICIDES FOR PLANTS LUCKY LTD. (KR) 1996-05-07 US disclosed
EP-0639574-A1 2-aminothiazolecarboxamide derivatives, processes for their preparation and their use for controlling phytopathogenic organisms LUCKY LTD. (KR) 1995-02-22 EP disclosed