Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 1/20 | 0.50 |
| ▸ | CYP19A1 | P11511 | 9/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | SLC5A2 | P31639 | 1/20 | 0.38 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.38 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.38 |
| ▸ | MIF | P14174 | 1/20 | 0.37 |
| ▸ | ESR1 | P03372 | 2/20 | 0.37 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.37 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.37 |
| ▸ | TACR2 | P21452 | 2/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | SHBG | P04278 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9850641 | 1.00 | KCNH2 (0.50) | KCNH2CYP19A1ALDH1A1SLC5A2GABRA2 | |
| SCHEMBL941277 | 0.98 | KCNH2 (0.47) | KCNH2CYP19A1ALDH1A1SLC5A2GABRA2 | |
| SCHEMBL9215468 | 0.92 | ALDH1A1 (0.46) | KCNH2CYP19A1ALDH1A1SLC5A2GABRA2 | |
| SCHEMBL22941955 | 0.88 | KCNH2 (0.61) | KCNH2CYP19A1ALDH1A1MIFESR1 | |
| SCHEMBL12356537 | 0.86 | KCNH2 (0.59) | KCNH2CYP19A1ALDH1A1MIFESR1 | |
| SCHEMBL3182612 | 0.84 | ALDH1A1 (0.48) | CYP19A1ALDH1A1SLC5A2GABRA2GABRB2 | |
| SCHEMBL25801711 | 0.82 | KCNH2 (0.52) | KCNH2CYP19A1ALDH1A1SLC5A2MIF | |
| SCHEMBL14722461 | 0.76 | KCNH2 (0.48) | KCNH2CYP19A1ALDH1A1MIFESR1 | |
| SCHEMBL4592210 | 0.76 | ALDH1A1 (0.46) | ALDH1A1SLC5A2 | |
| SCHEMBL12668129 | 0.76 | KCNH2 (0.48) | KCNH2CYP19A1ALDH1A1MIFESR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0546338-B1 | Mesomorphic compound, liquid crystal composition, liquid crystal device, display apparatus and display method | CANON KK (JP) | 1998-02-04 | — | — | EP | disclosed |
| US-5385692-A | Improved response | CANON KABUSHIKI KAISHA (JP) | 1995-01-31 | — | — | US | disclosed |
| EP-0546338-A1 | Mesomorphic compound, liquid crystal composition, liquid crystal device, display apparatus and display method | CANON KABUSHIKI KAISHA (JP) | 1993-06-16 | — | — | EP | disclosed |