SCHEMBL8551746

SCHEMBL8551746

C=CC(=O)OC(C)c1ccc(C(=O)O)c(C(=O)O)c1C(C)OC(=O)C=C

nearest known ligand 0.33

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
HCAR2 Q8TDS4 1/20 0.33
ALDH1A1 P00352 1/20 0.33
ACE2 Q9BYF1 1/20 0.32
GRM1 Q13255 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5175650 0.90 HCAR2 (0.36) HCAR2ALDH1A1
SCHEMBL10934497 0.87 HCAR2 (0.31) HCAR2ALDH1A1
SCHEMBL1564579 0.83 HCAR2 (0.38) HCAR2ALDH1A1
SCHEMBL21314239 0.82 HCAR2 (0.33) HCAR2ALDH1A1
SCHEMBL23071482 0.81 PTPN1 (0.30) HCAR2
SCHEMBL22749434 0.81 HCAR2 (0.30) HCAR2
SCHEMBL23071484 0.81 ACE2 (0.32) HCAR2ACE2
SCHEMBL2459421 0.80 ALDH1A1 (0.31) ALDH1A1ACE2
SCHEMBL2767683 0.80 ALDH1A1 (0.31) ALDH1A1ACE2
SCHEMBL10391375 0.80 THRB (0.40) ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0724503-B1 ABRASIVE ARTICLES INCORPORATING ADDITION POLYMERIZABLE RESINS AND REACTIVE DILUENTS, AND METHODS OF MAKING SAID ABRASIVE ARTICLES MINNESOTA MINING & MFG (US) 1998-11-11 EP disclosed
US-5736747-A SOLUBLE CURING AGENTS FOR PHENOLIC RESINS OR PHOTOPOLYMERIZABLE MONOMER MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1998-04-07 US disclosed
US-5733648-A FOR AMINOPLASTS MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1998-03-31 US disclosed
US-5710281-A Organic compounds suitable as reactive diluents and binder precursor compositions including same MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1998-01-20 US disclosed
US-5709935-A ACRYLATE FUNCTIONAL DILUENTS WHICH SOLUBILIZE AMINO RESINS MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1998-01-20 US disclosed
US-5667842-A Abrasive articles incorporating addition polymerizable resins and reactive diluents, and methods of making said abrasive articles MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1997-09-16 US disclosed
US-5580647-A OPEN NON-WOVEN MAT HAVING FIBERS JOINED AT POINTS OF CONTACT BY BINDER FROM ADDITION POLYMERIZABLE BINDER PRECURSOR MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1996-12-03 US disclosed
EP-0724503-A1 ABRASIVE ARTICLES INCORPORATING ADDITION POLYMERIZABLE RESINS AND REACTIVE DILUENTS, AND METHODS OF MAKING SAID ABRASIVE ARTICLES MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1996-08-07 EP disclosed
US-5523152-A Organic compounds suitable as reactive diluents, and binder precursor compositions including same MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1996-06-04 US disclosed
WO-1995011774-A1 ABRASIVE ARTICLES INCORPORATING ADDITION POLYMERIZABLE RESINS AND REACTIVE DILUENTS, AND METHODS OF MAKING SAID ABRASIVE ARTICLES MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1995-05-04 WO disclosed
US-4070497-A Process of applying and curing a plurality of coatings PPG INDUSTRIES, INC. (US) 1978-01-24 US disclosed