SCHEMBL8551752

SCHEMBL8551752

Cc1nc(NC2CC2)sc1C(=O)Cl

nearest known ligand 0.44

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.44
CCNA2 P20248 2/20 0.42
CDK2 P24941 2/20 0.42
ALDH1A1 P00352 3/20 0.41
PI4KB Q9UBF8 2/20 0.41
NPC1 O15118 3/20 0.40
RAB9A P51151 3/20 0.40
LCK P06239 1/20 0.39
CYP1A2 P05177 1/20 0.39
GAA P10253 1/20 0.39
CYP2C9 P11712 1/20 0.39
RXFP1 Q9HBX9 1/20 0.39
L3MBTL1 Q9Y468 2/20 0.39
MEN1 O00255 2/20 0.39
KMT2A Q03164 2/20 0.39
POLB P06746 2/20 0.38
MAPT P10636 1/20 0.38
SMN1; SMN2 Q16637 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17454473 0.85 RXFP1 (0.54) LMNAALDH1A1NPC1RAB9ACYP1A2
SCHEMBL8553614 0.85 ALDH1A1 (0.47) LMNACCNA2CDK2ALDH1A1PI4KB
Hydrochloric Acid SCHEMBL8551755 0.84 ALDH1A1 (0.46) LMNACCNA2CDK2ALDH1A1PI4KB
SCHEMBL17452592 0.81 CYP1A2 (0.47) LMNACCNA2CDK2ALDH1A1PI4KB
SCHEMBL8556702 0.73 MAPK14 (0.48) CCNA2CDK2ALDH1A1NPC1RAB9A
SCHEMBL8554355 0.73 PIK3CG (0.43) ALDH1A1NPC1RAB9ALCKCYP1A2
SCHEMBL8557699 0.72 LCK (0.58) LMNAALDH1A1LCKCYP1A2GAA
SCHEMBL3902955 0.71 ALDH1A1 (0.42) LMNACCNA2CDK2ALDH1A1NPC1
SCHEMBL20452492 0.71 ALDH1A1 (0.48) LMNACCNA2CDK2ALDH1A1PI4KB
SCHEMBL18454013 0.71 ALDH1A1 (0.48) LMNACCNA2CDK2ALDH1A1PI4KB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0639574-B1 2-aminothiazolecarboxamide derivatives, processes for their preparation and their use for controlling phytopathogenic organisms LUCKY LTD (KR) 1998-06-10 EP disclosed
US-5514643-A FUNGICIDES FOR PLANTS LUCKY LTD. (KR) 1996-05-07 US disclosed
EP-0639574-A1 2-aminothiazolecarboxamide derivatives, processes for their preparation and their use for controlling phytopathogenic organisms LUCKY LTD. (KR) 1995-02-22 EP disclosed