Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 1/20 | 0.50 |
| ▸ | F10 | P00742 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.45 |
| ▸ | TTR | P02766 | 2/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.44 |
| ▸ | PARP3 | Q9Y6F1 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | CASP6 | P55212 | 1/20 | 0.43 |
| ▸ | ALDH1A3 | P47895 | 1/20 | 0.41 |
| ▸ | MPO | P05164 | 1/20 | 0.41 |
| ▸ | TPO | P07202 | 1/20 | 0.41 |
| ▸ | EPX | P11678 | 1/20 | 0.41 |
| ▸ | LPO | P22079 | 1/20 | 0.41 |
| ▸ | STS | P08842 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8549986 | 0.85 | ALDH1A1 (0.47) | F2F10ALDH1A1KDM4ELMNA | |
| SCHEMBL1508467 | 0.84 | HSD17B10 (0.50) | ALDH1A1KDM4ELMNASMN1; SMN2CYP2A6 | |
| SCHEMBL9265274 | 0.84 | TTR (0.65) | ALDH1A1KDM4ELMNASMN1; SMN2TTR | |
| SCHEMBL6142404 | 0.81 | TTR (0.47) | ALDH1A1KDM4ELMNASMN1; SMN2TTR | |
| SCHEMBL30378054 | 0.81 | TTR (0.47) | ALDH1A1KDM4ELMNASMN1; SMN2CYP2A6 | |
| SCHEMBL755560 | 0.81 | TTR (0.47) | ALDH1A1KDM4ELMNASMN1; SMN2CYP2A6 | |
| SCHEMBL29984 | 0.81 | ALDH1A1 (0.43) | F2F10ALDH1A1KDM4ELMNA | |
| SCHEMBL24512660 | 0.80 | TTR (0.60) | ALDH1A1KDM4ESMN1; SMN2TTRHSD17B10 | |
| SCHEMBL30758635 | 0.79 | ALDH1A1 (0.49) | ALDH1A1KDM4ELMNASMN1; SMN2CYP2A6 | |
| SCHEMBL2317083 | 0.79 | ALDH1A1 (0.49) | ALDH1A1KDM4ELMNASMN1; SMN2CYP2A6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0696585-B1 | NOVEL BISOXADIAZOLIDINE DERIVATIVE | YAMANOUCHI PHARMA CO LTD (JP) | 1998-12-16 | — | — | EP | disclosed |
| US-5643931-A | ANTIDIABETIC AGENTS | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) | 1997-07-01 | — | — | US | disclosed |
| EP-0696585-A1 | NOVEL BISOXADIAZOLIDINE DERIVATIVE | YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) | 1996-02-14 | — | — | EP | disclosed |