SCHEMBL8551820

SCHEMBL8551820

C=CC(=O)OC(C)OC(C)N1C(=O)C2CCCCC2C1=O

nearest known ligand 0.33

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 2/20 0.33
NPC1 O15118 1/20 0.33
RAB9A P51151 1/20 0.33
KDM4E B2RXH2 3/20 0.32
LMNA P02545 2/20 0.32
ALDH1A1 P00352 1/20 0.32
GLA P06280 1/20 0.31
CNR1 P21554 1/20 0.31
HTT P42858 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL782188 0.90 SMN1; SMN2 (0.36) SMN1; SMN2NPC1RAB9AKDM4ELMNA
SCHEMBL8552466 0.77 HTT (0.36) SMN1; SMN2NPC1RAB9AKDM4ELMNA
SCHEMBL8551822 0.76 TSHR (0.38) SMN1; SMN2NPC1RAB9AKDM4ELMNA
SCHEMBL1146669 0.76 ALDH1A1 (0.43) SMN1; SMN2KDM4ELMNAALDH1A1HTT
SCHEMBL23581828 0.74 HTT (0.39) SMN1; SMN2NPC1RAB9AKDM4ELMNA
SCHEMBL8553842 0.74 NPC1 (0.33) SMN1; SMN2NPC1RAB9ALMNAALDH1A1
SCHEMBL12098030 0.73 SMN1; SMN2 (0.36) SMN1; SMN2NPC1RAB9AKDM4ELMNA
SCHEMBL8550911 0.72 CYP3A4 (0.30)
SCHEMBL14776926 0.71 TSHR (0.33)
SCHEMBL4940010 0.70 TSHR (0.35)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0724503-B1 ABRASIVE ARTICLES INCORPORATING ADDITION POLYMERIZABLE RESINS AND REACTIVE DILUENTS, AND METHODS OF MAKING SAID ABRASIVE ARTICLES MINNESOTA MINING & MFG (US) 1998-11-11 EP disclosed
US-5736747-A SOLUBLE CURING AGENTS FOR PHENOLIC RESINS OR PHOTOPOLYMERIZABLE MONOMER MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1998-04-07 US disclosed
US-5733648-A FOR AMINOPLASTS MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1998-03-31 US disclosed
US-5710281-A Organic compounds suitable as reactive diluents and binder precursor compositions including same MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1998-01-20 US disclosed
US-5709935-A ACRYLATE FUNCTIONAL DILUENTS WHICH SOLUBILIZE AMINO RESINS MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1998-01-20 US disclosed
US-5667842-A Abrasive articles incorporating addition polymerizable resins and reactive diluents, and methods of making said abrasive articles MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1997-09-16 US disclosed
US-5580647-A OPEN NON-WOVEN MAT HAVING FIBERS JOINED AT POINTS OF CONTACT BY BINDER FROM ADDITION POLYMERIZABLE BINDER PRECURSOR MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1996-12-03 US disclosed
EP-0724503-A1 ABRASIVE ARTICLES INCORPORATING ADDITION POLYMERIZABLE RESINS AND REACTIVE DILUENTS, AND METHODS OF MAKING SAID ABRASIVE ARTICLES MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1996-08-07 EP disclosed
US-5523152-A Organic compounds suitable as reactive diluents, and binder precursor compositions including same MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1996-06-04 US disclosed
WO-1995011774-A1 ABRASIVE ARTICLES INCORPORATING ADDITION POLYMERIZABLE RESINS AND REACTIVE DILUENTS, AND METHODS OF MAKING SAID ABRASIVE ARTICLES MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1995-05-04 WO disclosed