SCHEMBL8552466

SCHEMBL8552466

C=CC(=O)OC(CC)N1C(=O)C2CCCCC2C1=O

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTT P42858 1/20 0.36
LMNA P02545 4/20 0.33
KDM4E B2RXH2 3/20 0.33
SMN1; SMN2 Q16637 3/20 0.33
ALDH1A1 P00352 3/20 0.33
RAB9A P51151 2/20 0.32
TDP1 Q9NUW8 2/20 0.32
GLA P06280 1/20 0.31
KMT2A Q03164 2/20 0.31
NPC1 O15118 1/20 0.31
PPOX P50336 1/20 0.31
MAPT P10636 1/20 0.31
MEN1 O00255 1/20 0.31
MAPK1 P28482 1/20 0.31
TP53 P04637 1/20 0.30
PDE4A P27815 1/20 0.30
PDE4B Q07343 1/20 0.30
PDE4C Q08493 1/20 0.30
PDE4D Q08499 1/20 0.30
TSHR P16473 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL782188 0.82 SMN1; SMN2 (0.36) HTTLMNAKDM4ESMN1; SMN2ALDH1A1
SCHEMBL8659880 0.81 HTT (0.36) HTTLMNAKDM4ESMN1; SMN2ALDH1A1
SCHEMBL8551820 0.77 SMN1; SMN2 (0.33) HTTLMNAKDM4ESMN1; SMN2ALDH1A1
SCHEMBL23581828 0.75 HTT (0.39) HTTLMNAKDM4ESMN1; SMN2ALDH1A1
SCHEMBL16694105 0.72 TSHR (0.36) ALDH1A1TP53TSHR
SCHEMBL8553842 0.72 NPC1 (0.33) HTTLMNASMN1; SMN2ALDH1A1RAB9A
SCHEMBL8551822 0.72 TSHR (0.38) HTTLMNAKDM4ESMN1; SMN2ALDH1A1
SCHEMBL27815733 0.70 LMNA (0.50) LMNATSHR
SCHEMBL9838175 0.70 LMNA (0.40) LMNAKDM4EALDH1A1GLAMAPK1
SCHEMBL10349085 0.70 TSHR (0.34) ALDH1A1MAPTMAPK1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0724503-B1 ABRASIVE ARTICLES INCORPORATING ADDITION POLYMERIZABLE RESINS AND REACTIVE DILUENTS, AND METHODS OF MAKING SAID ABRASIVE ARTICLES MINNESOTA MINING & MFG (US) 1998-11-11 EP disclosed
US-5736747-A SOLUBLE CURING AGENTS FOR PHENOLIC RESINS OR PHOTOPOLYMERIZABLE MONOMER MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1998-04-07 US disclosed
US-5733648-A FOR AMINOPLASTS MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1998-03-31 US disclosed
US-5710281-A Organic compounds suitable as reactive diluents and binder precursor compositions including same MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1998-01-20 US disclosed
US-5709935-A ACRYLATE FUNCTIONAL DILUENTS WHICH SOLUBILIZE AMINO RESINS MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1998-01-20 US disclosed
US-5580647-A OPEN NON-WOVEN MAT HAVING FIBERS JOINED AT POINTS OF CONTACT BY BINDER FROM ADDITION POLYMERIZABLE BINDER PRECURSOR MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1996-12-03 US disclosed
EP-0724503-A1 ABRASIVE ARTICLES INCORPORATING ADDITION POLYMERIZABLE RESINS AND REACTIVE DILUENTS, AND METHODS OF MAKING SAID ABRASIVE ARTICLES MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1996-08-07 EP disclosed
US-5523152-A Organic compounds suitable as reactive diluents, and binder precursor compositions including same MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1996-06-04 US disclosed
WO-1995011774-A1 ABRASIVE ARTICLES INCORPORATING ADDITION POLYMERIZABLE RESINS AND REACTIVE DILUENTS, AND METHODS OF MAKING SAID ABRASIVE ARTICLES MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1995-05-04 WO disclosed