Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.45 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 3/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | GMNN | O75496 | 1/20 | 0.36 |
| ▸ | EGFR | P00533 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | FYN | P06241 | 1/20 | 0.36 |
| ▸ | CA3 | P07451 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31018097 | 1.00 | TSHR (0.45) | TSHRGABRA1GABRB2POLBTRPA1 | |
| SCHEMBL3571847 | 1.00 | TSHR (0.45) | TSHRGABRA1GABRB2POLBTRPA1 | |
| SCHEMBL5934663 | 0.89 | TSHR (0.50) | TSHRGABRA1GABRB2POLBHPGD | |
| SCHEMBL28331376 | 0.85 | TSHR (0.47) | TSHRGABRA1GABRB2POLBHPGD | |
| SCHEMBL29270230 | 0.83 | TSHR (0.48) | TSHRGABRA1GABRB2POLBHPGD | |
| SCHEMBL15799114 | 0.83 | TSHR (0.48) | TSHRGABRA1GABRB2POLBHPGD | |
| SCHEMBL29378518 | 0.83 | TSHR (0.48) | TSHRGABRA1GABRB2POLBHPGD | |
| SCHEMBL7047933 | 0.83 | TSHR (0.48) | TSHRGABRA1GABRB2POLBHPGD | |
| SCHEMBL940014 | 0.82 | TSHR (0.53) | TSHRGABRA1GABRB2POLBHPGD | |
| SCHEMBL21447694 | 0.80 | GABRA1 (0.52) | TSHRGABRA1GABRB2POLBHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 41 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115980205-B | Quantitative and/or qualitative method for simultaneously measuring 54 hair dyes in hair dye product | 江苏省食品药品监督检验研究院 | 2025-04-22 | — | — | CN | claimed |
| EP-1473025-B1 | Dyeing composition containing 2-chloro-6-methyl-3-aminophenol and an associative polymer | OREAL (FR) | 2012-03-28 | — | — | EP | claimed |
| EP-1066021-A1 | NAPHTHALENE CATIONIC COUPLER FOR OXIDATION DYEING OF KERATIN FIBER | L'OREAL (FR) | 2001-01-10 | — | — | EP | claimed |
| EP-1064268-A1 | NOVEL CATIONIC COMPOUNDS, THEIR USE AS COUPLING AGENTS FOR OXIDATION DYEING OF KERATINOUS FIBRES, DYEING COMPOSITIONS AND DYEING METHODS | L'OREAL (FR) | 2001-01-03 | — | — | EP | claimed |
| WO-2000042980-A1 | NAPHTHALENE CATIONIC COUPLER FOR OXIDATION DYEING OF KERATIN FIBER | L'OREAL (FR) | 2000-07-27 | — | — | WO | claimed |
| EP-0998258-A1 | OXIDATION DYEING COMPOSITION FOR KERATIN FIBRES | L'OREAL (FR) | 2000-05-10 | — | — | EP | claimed |
| WO-1999048875-A1 | NOVEL CATIONIC COMPOUNDS, THEIR USE AS COUPLING AGENTS FOR OXIDATION DYEING OF KERATINOUS FIBRES, DYEING COMPOSITIONS AND DYEING METHODS | L'OREAL (FR) | 1999-09-30 | — | — | WO | claimed |
| WO-1999017728-A1 | OXIDATION DYEING COMPOSITION FOR KERATIN FIBRES | L'OREAL (FR) | 1999-04-15 | — | — | WO | claimed |
| WO-1997013494-A1 | COMPOSITION FOR OXIDATION DYEING KERATIN FIBRES, CONTAINING 2-AMINO 3-HYDROXY PYRIDINE AND AN OXIDATION BASE, AND DYEING METHOD | L'OREAL (FR) | 1997-04-17 | — | — | WO | claimed |
| US-12636241-B1 | Method and composition for oxidative hair coloring | WELLA OPERATIONS US LLC (US) | 2026-05-26 | — | — | US | disclosed |
| EP-4552630-A1 | RESORCINOL FREE PERMANENT HAIR COLOR COMPOSITION AND METHOD | Wella Operations US, LLC (US) | 2025-05-14 | — | — | EP | disclosed |
| EP-4548908-A1 | PERMANENT OXIDATIVE HAIR-COLOURING COMPOSITIONS | Beauty & Business SpA (IT) | 2025-05-07 | — | — | EP | disclosed |
| US-20250134788-A1 | PERMANENT OXIDATIVE HAIR-COLORING COMPOSITIONS | BEAUTY & BUSINESS S.P.A. (IT) | 2025-05-01 | — | — | US | disclosed |
| CN-115980205-B | Quantitative and/or qualitative method for simultaneously measuring 54 hair dyes in hair dye product | 江苏省食品药品监督检验研究院 | 2025-04-22 | — | — | CN | disclosed |
| EP-0900074-A1 | KERATIN FIBRE DYE COMPOSITIONS CONTAINING PYRAZOLIN-3,5-DIONE COMPOUNDS, USE THEREOF AS DYE COUPLERS, AND DYEING METHOD | L'OREAL (FR) | 1999-03-10 | — | — | EP | disclosed |
| EP-0893985-A1 | KERATIN FIBRE DYE COMPOSITIONS CONTAINING IMIDAZOLO-AZOLE COMPOUNDS, USE THEREOF AS DYE COUPLERS, AND DYEING METHOD | L'OREAL (FR) | 1999-02-03 | — | — | EP | disclosed |
| EP-0889718-A1 | KERATIN FIBRE DYE COMPOSITIONS CONTAINING PYRROLO-AZOLE COMPOUNDS, USE THEREOF AS COUPLERS, AND DYEING METHOD | L'OREAL (FR) | 1999-01-13 | — | — | EP | disclosed |
| WO-1997035552-A1 | KERATIN FIBRE DYE COMPOSITIONS CONTAINING IMIDAZOLO-AZOLE COMPOUNDS, USE THEREOF AS DYE COUPLERS, AND DYEING METHOD | L'OREAL (FR) | 1997-10-02 | — | — | WO | disclosed |
| WO-1997035554-A1 | KERATIN FIBRE DYE COMPOSITIONS CONTAINING PYRROLO-AZOLE COMPOUNDS, USE THEREOF AS COUPLERS, AND DYEING METHOD | L'OREAL (FR) | 1997-10-02 | — | — | WO | disclosed |
| WO-1997035553-A1 | KERATIN FIBRE DYE COMPOSITIONS CONTAINING PYRAZOLIN-3,5-DIONE COMPOUNDS, USE THEREOF AS DYE COUPLERS, AND DYEING METHOD | L'OREAL (FR) | 1997-10-02 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12636241-B1 | Method and composition for oxidative hair coloring | POLB, DAO, ALPP | TSHR 2634/4885GABRA1 3449/4885GABRB2 1750/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.