Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 4/20 | 0.49 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.49 |
| ▸ | RXRA | P19793 | 10/20 | 0.47 |
| ▸ | RXRB | P28702 | 10/20 | 0.47 |
| ▸ | RXRG | P48443 | 6/20 | 0.47 |
| ▸ | NR4A2 | P43354 | 5/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.42 |
| ▸ | C5 | P01031 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.42 |
| ▸ | DRD2 | P14416 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.42 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.42 |
| ▸ | HTR2A | P28223 | 1/20 | 0.42 |
| ▸ | HTR2C | P28335 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8549476 | 0.90 | PTGS2 (0.51) | PTGS2PTGS1RXRARXRBRXRG | |
| SCHEMBL7503309 | 0.90 | PTGS1 (0.48) | PTGS2PTGS1RXRARXRBRXRG | |
| SCHEMBL7505707 | 0.90 | PTGS1 (0.48) | PTGS2PTGS1RXRARXRBRXRG | |
| SCHEMBL7503923 | 0.87 | PTGS2 (0.55) | PTGS2PTGS1CA12CA1CA2 | |
| SCHEMBL8549353 | 0.83 | PTGS2 (0.52) | PTGS2PTGS1RXRARXRBRXRG | |
| SCHEMBL7501777 | 0.82 | PTGS2 (0.58) | PTGS2PTGS1CA12CA1CA2 | |
| SCHEMBL9037846 | 0.82 | NR4A2 (0.49) | PTGS2PTGS1RXRARXRBRXRG | |
| SCHEMBL6028370 | 0.81 | PTGS1 (0.50) | PTGS2PTGS1RXRARXRBRXRG | |
| SCHEMBL6026236 | 0.81 | RXRA (0.40) | PTGS2PTGS1RXRARXRBRXRG | |
| SCHEMBL7510284 | 0.81 | PTGS2 (0.57) | PTGS2PTGS1CA12CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0825989-A1 | SUBSTITUTED OXAZOLES FOR THE TREATMENT OF INFLAMMATION | G.D. SEARLE & CO. (US) | 1998-03-04 | — | — | EP | disclosed |