Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FBP1 | P09467 | 15/20 | 0.48 |
| ▸ | VCP | P55072 | 3/20 | 0.46 |
| ▸ | EGFR | P00533 | 2/20 | 0.43 |
| ▸ | ABL1 | P00519 | 1/20 | 0.43 |
| ▸ | ABL2 | P42684 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8642563 | 1.00 | FBP1 (0.48) | FBP1VCPEGFRABL1ABL2 | |
| SCHEMBL11034872 | 0.79 | FBP1 (0.50) | FBP1VCPEGFRABL1ABL2 | |
| SCHEMBL3272796 | 0.79 | MAPT (0.43) | ALDH1A1MAPT | |
| SCHEMBL9004983 | 0.79 | MAPT (0.43) | ALDH1A1MAPT | |
| SCHEMBL8138642 | 0.78 | FBP1 (0.48) | FBP1VCPEGFRABL1ABL2 | |
| SCHEMBL8138639 | 0.78 | FBP1 (0.48) | FBP1VCPEGFRABL1ABL2 | |
| SCHEMBL1225186 | 0.74 | MAPT (0.46) | ALDH1A1MAPTLMNA | |
| SCHEMBL1225185 | 0.74 | MAPT (0.46) | ALDH1A1MAPTLMNA | |
| SCHEMBL9779324 | 0.71 | MAOB (0.59) | ALDH1A1MAPTLMNASMN1; SMN2 | |
| SCHEMBL9779320 | 0.71 | MAOB (0.59) | ALDH1A1MAPTLMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0833630-A4 | NOVEL BENZOPYRAN COMPOUNDS AND METHODS FOR THEIR USE | SUGEN INC (US) | 1998-09-02 | — | — | EP | disclosed |
| US-5763470-A | Benzopyran compounds and methods for their use | SUGEN INC. (US) | 1998-06-09 | — | — | US | disclosed |
| EP-0833630-A1 | NOVEL BENZOPYRAN COMPOUNDS AND METHODS FOR THEIR USE | Sugen, Inc. (US) | 1998-04-08 | — | — | EP | disclosed |
| WO-1996040110-A1 | NOVEL BENZOPYRAN COMPOUNDS AND METHODS FOR THEIR USE | SUGEN, INC. (US) | 1996-12-19 | — | — | WO | disclosed |