SCHEMBL8138642

SCHEMBL8138642

O=[N+]([O-])C=Cc1csc(Br)c1

nearest known ligand 0.48

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
FBP1 P09467 16/20 0.48
VCP P55072 3/20 0.47
EGFR P00533 2/20 0.43
ABL1 P00519 1/20 0.43
ABL2 P42684 1/20 0.43
ALDH1A1 P00352 1/20 0.40
LMNA P02545 1/20 0.40
MAPT P10636 1/20 0.40
SMN1; SMN2 Q16637 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8138639 1.00 FBP1 (0.48) FBP1VCPEGFRABL1ABL2
SCHEMBL11034872 0.79 FBP1 (0.50) FBP1VCPEGFRABL1ABL2
SCHEMBL8642563 0.78 FBP1 (0.48) FBP1VCPEGFRABL1ABL2
SCHEMBL8552036 0.78 FBP1 (0.48) FBP1VCPEGFRABL1ABL2
SCHEMBL28856889 0.72 FBP1 (0.55) FBP1VCPEGFRABL1ABL2
SCHEMBL28341931 0.72 FBP1 (0.55) FBP1VCPEGFRABL1ABL2
SCHEMBL792983 0.72 FBP1 (0.41) FBP1VCPEGFRABL1ABL2
SCHEMBL792984 0.72 FBP1 (0.41) FBP1VCPEGFRABL1ABL2
SCHEMBL154878 0.69
SCHEMBL421634 0.68 FBP1 (0.64) FBP1VCPEGFRABL1ABL2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0641794-B1 Thienyl- and furylpyrrole derivatives, their preparation and their use as insecticides and acaricides AMERICAN CYANAMID CO (US) 2000-10-11 EP disclosed
US-5563166-A Thienyl- and furylpyrrole fungicidal agents AMERICAN CYANAMID CO. (US) 1996-10-08 US disclosed
US-5492925-A PROTECTING PLANTS AMERICAN CYANAMID COMPANY (US) 1996-02-20 US disclosed
US-5480902-A Thienylpyrrole fungicidal agents AMERICAN CYANAMID COMPANY (US) 1996-01-02 US disclosed
EP-0641794-A1 Thienyl- and furylpyrrole derivatives, their preparation and their use as insecticides and acaricides AMERICAN CYANAMID COMPANY (US) 1995-03-08 EP disclosed