Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 3/20 | 0.54 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.54 |
| ▸ | GRM5 | P41594 | 4/20 | 0.45 |
| ▸ | CNR1 | P21554 | 1/20 | 0.43 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.42 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14996602 | 0.78 | CNR1 (0.48) | GRM5CNR1NR1H2NR1H3MEN1 | |
| SCHEMBL14996603 | 0.78 | CNR1 (0.48) | GRM5CNR1NR1H2NR1H3MEN1 | |
| SCHEMBL27945254 | 0.75 | CNR1 (0.49) | GRM5CNR1NR1H2NR1H3MEN1 | |
| SCHEMBL20074757 | 0.75 | CNR1 (0.46) | GRM5CNR1NR1H2NR1H3MEN1 | |
| SCHEMBL8549963 | 0.74 | SLC34A1 (0.39) | PTGS1PTGS2CNR1NR1H2NR1H3 | |
| SCHEMBL13066524 | 0.74 | MEN1 (0.46) | PTGS1PTGS2GRM5CNR1NR1H2 | |
| SCHEMBL12856425 | 0.74 | GRM5 (0.47) | GRM5CNR1NR1H2NR1H3KDM4E | |
| SCHEMBL13066522 | 0.74 | SMN1; SMN2 (0.46) | PTGS1PTGS2GRM5NR1H2NR1H3 | |
| SCHEMBL13430367 | 0.72 | POLB (0.54) | PTGS1PTGS2NR1H2NR1H3KDM4E | |
| SCHEMBL6013971 | 0.71 | PTGS2 (1.00) | PTGS1PTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0846105-A1 | HERBICIDAL SUBSTITUTED 3-ARYL-PYRAZOLES | MONSANTO COMPANY (US) | 1998-06-10 | — | — | EP | disclosed |
| US-5675017-A | REACTING VINY ETHER DERIVATIVE WITH HYDRZINE OR SUBSTITUTED HYDRAZINE TO FORM A CHEMICAL INTERMEDIATE, REACTING INTERMEDIATE WITH SUBSTITUTED HALIDE OR DIALKYL SULFATE | MONSANTO COMPANY (US) | 1997-10-07 | — | — | US | disclosed |
| US-5672715-A | Herbicidal substituted 3-aryl-pyrazoles | MONSANTO COMPANY (US) | 1997-09-30 | — | — | US | disclosed |
| US-5668088-A | Herbicidal substituted 3-aryl-pyrazoles | MONSANTO COMPANY (US) | 1997-09-16 | — | — | US | disclosed |
| WO-1996040643-A1 | HERBICIDAL SUBSTITUTED 3-ARYL-PYRAZOLES | MONSANTO COMPANY (US) | 1996-12-19 | — | — | WO | disclosed |