Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 1/20 | 0.47 |
| ▸ | SLC34A1 | Q06495 | 2/20 | 0.45 |
| ▸ | TDP2 | O95551 | 1/20 | 0.43 |
| ▸ | PDE2A | O00408 | 7/20 | 0.42 |
| ▸ | CNR1 | P21554 | 1/20 | 0.42 |
| ▸ | CNR2 | P34972 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.41 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.40 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.40 |
| ▸ | KIF11 | P52732 | 1/20 | 0.39 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.38 |
| ▸ | DYRK2 | Q92630 | 1/20 | 0.38 |
| ▸ | PDE5A | O76074 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12856369 | 0.85 | NPC1 (0.40) | GRM5CNR1KDM4ENPC1RAB9A | |
| SCHEMBL14996669 | 0.83 | PDE2A (0.49) | GRM5SLC34A1TDP2PDE2AKDM4E | |
| SCHEMBL12859333 | 0.81 | TDP2 (0.39) | GRM5SLC34A1TDP2PDE2ACNR1 | |
| SCHEMBL14996540 | 0.81 | L3MBTL1 (0.44) | GRM5SLC34A1TDP2CNR1KDM4E | |
| SCHEMBL14996602 | 0.81 | CNR1 (0.48) | GRM5SLC34A1TDP2PDE2ACNR1 | |
| SCHEMBL20074764 | 0.81 | GRM5 (0.47) | GRM5SLC34A1TDP2PDE2AKDM4E | |
| SCHEMBL12871648 | 0.80 | SLC34A1 (0.41) | GRM5SLC34A1TDP2PDE2ASIGMAR1 | |
| SCHEMBL14996671 | 0.79 | HSD11B1 (0.43) | PDE2A | |
| SCHEMBL14996665 | 0.78 | NR1H2 (0.44) | GRM5SLC34A1KDM4ENPC1RAB9A | |
| SCHEMBL13066524 | 0.77 | MEN1 (0.46) | GRM5SLC34A1TDP2PDE2ACNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2281810-B1 | AMIDE COMPOUNDS, PREPARATION METHODS AND USES THEREOF | SINOCHEM CORP (CN) | 2014-02-19 | — | — | EP | disclosed |
| US-8455398-B2 | Amide compounds, preparation methods and uses thereof | SINOCHEM CORPORATION (CN) | 2013-06-04 | — | — | US | disclosed |
| EP-2281810-A1 | AMIDE COMPOUNDS, PREPARATION METHODS AND USES THEREOF | Sinochem Corporation (CN) | 2011-02-09 | — | — | EP | disclosed |