⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Piracetam SCHEMBL20172 | 0.87 | TSHR (1.00) | — | |
| Piracetam SCHEMBL6140872 | 0.87 | TSHR (1.00) | — | |
| SCHEMBL24263535 | 0.85 | TSHR (0.89) | — | |
| Piracetam SCHEMBL28423013 | 0.85 | TSHR (0.96) | — | |
| SCHEMBL1532937 | 0.84 | TSHR (0.85) | — | |
| SCHEMBL13315045 | 0.80 | TSHR (0.57) | — | |
| SCHEMBL6361223 | 0.79 | TSHR (0.50) | — | |
| SCHEMBL43400 | 0.79 | — | — | |
| SCHEMBL11315834 | 0.77 | — | — | |
| SCHEMBL7771566 | 0.77 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0840725-A1 | AZETIDINONE DERIVATIVES FOR THE TREATMENT OF ATHEROSCLEROSIS | SMITHKLINE BEECHAM PLC (GB) | 1998-05-13 | — | — | EP | disclosed |
| EP-0799200-A1 | SUBSTITUTED AZETIDIN-2-ONES FOR TREATMENT OF ATHEROSCLEROSIS | SMITHKLINE BEECHAM PLC (GB) | 1997-10-08 | — | — | EP | disclosed |
| WO-1997002242-A1 | AZETIDINONE DERIVATIVES FOR THE TREATMENT OF ATHEROSCLEROSIS | SMITHKLINE BEECHAM PLC (GB) | 1997-01-23 | — | — | WO | disclosed |
| EP-0171159-B1 | SUBSTITUTED AZETIDINONE COMPOUNDS, THEIR PREPARATION, AND MEDICAMENTS CONTAINING THEM | YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) | 1990-05-30 | — | — | EP | disclosed |
| US-4719207-A | CENTRAL NERVOUS SYSTEM | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) | 1988-01-12 | — | — | US | disclosed |
| EP-0171159-A1 | Substituted azetidinone compounds, their preparation, and medicaments containing them | YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) | 1986-02-12 | — | — | EP | disclosed |