Piracetam

Piracetam

SCHEMBL20172

NC(=O)CN1CCCC1=O

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 1.00
PIK3CD O00329 1/20 0.52
HTT P42858 1/20 0.51
KMT2A Q03164 2/20 0.49
SMN1; SMN2 Q16637 2/20 0.48
APEX1 P27695 1/20 0.47
BLM P54132 1/20 0.47
ALDH1A1 P00352 1/20 0.46
LMNA P02545 3/20 0.44
CA12 O43570 1/20 0.44
CA1 P00915 1/20 0.44
CA2 P00918 1/20 0.44
CA3 P07451 1/20 0.44
CA4 P22748 1/20 0.44
CA6 P23280 1/20 0.44
CA5A P35218 1/20 0.44
CA7 P43166 1/20 0.44
CA9 Q16790 1/20 0.44
CA13 Q8N1Q1 1/20 0.44
CA14 Q9ULX7 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Piracetam SCHEMBL6140872 1.00 TSHR (1.00) TSHRPIK3CDHTTKMT2ASMN1; SMN2
Piracetam SCHEMBL28423013 0.98 TSHR (0.96) TSHRPIK3CDHTTKMT2ASMN1; SMN2
SCHEMBL24263535 0.94 TSHR (0.89) TSHRPIK3CDHTTKMT2ASMN1; SMN2
SCHEMBL1532937 0.92 TSHR (0.85) TSHRPIK3CDHTTKMT2ASMN1; SMN2
SCHEMBL8552055 0.87
Piracetam SCHEMBL1756178 0.83 TSHR (0.69) TSHRHTTKMT2ASMN1; SMN2ALDH1A1
4,4'-Methylenedianiline SCHEMBL20770172 0.83 TSHR (0.69) TSHRPIK3CDHTTKMT2ASMN1; SMN2
SCHEMBL22446137 0.82 TSHR (0.69) TSHRPIK3CDHTTKMT2ASMN1; SMN2
SCHEMBL948990 0.81 TSHR (0.68) TSHRPIK3CDHTTKMT2ASMN1; SMN2
SCHEMBL9628927 0.81 TSHR (0.67) TSHRPIK3CDHTTKMT2ASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 9843 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4746864-A1 C5 KETONE COMPOSITIONS AND RELATED METHODS FOR TREATING METABOLIC DYSFUNCTION Keto Innovations, LLC (US) 2026-05-27 EP claimed
CN-116850183-B Methods and pharmaceutical compositions for treating myopia GRAND PHARMA (CHINA) Co.,Ltd. (CN) 2026-05-26 CN claimed
US-20260137654-A1 COMPOUNDS AND METHODS FOR TREATING AN EPILEPTIC DISORDER THE REGENTS OF THE UNIV OF CALIFORNIA (US) 2026-05-21 US claimed
EP-4744670-A1 POLYLACTIC ACID AND USE OF COPOLYMER THEREOF IN PREPARATION OF DRUG FOR PROMOTING NERVE GROWTH AND REPAIR Changchun Sinobiomaterials Co., Ltd. (CN) 2026-05-20 EP claimed
WO-2026090582-A1 COMPOSITIONS CONTAINING A NON-XANTHINE CNS STIMULANT OR NOOTROPIC AND BETA-HYDROXYBUTYRATE OR PRECURSOR FOR INCREASING NEUROLOGICAL AND PHYSIOLOGICAL PERFORMANCE AXCESS GLOBAL SCIENCES, LLC (US) 2026-04-30 WO claimed
US-20260097008-A1 ACETYL LEUCINE FOR USE IN TREATING NIEMANN-PICK DISEASE TYPE C INTRABIO INC. 2026-04-09 US claimed
US-20260083706-A1 5HT AGONISTS FOR TREATING DISORDERS UNIV CALIFORNIA (US) 2026-03-26 US claimed
EP-4712954-A1 C5 KETONE COMPOSITIONS AND RELATED METHODS FOR THERAPEUTIC AND PERFORMANCE SUPPLEMENTATION Keto Innovations, LLC (US) 2026-03-25 EP claimed
EP-4696377-A2 5HT AGONISTS FOR TREATING DISORDERS The Regents of the University of California (US) 2026-02-18 EP claimed
US-12498384-B2 Biomarkers and methods for evaluation and treatment of epileptic vs non-epileptic seizures / no seizures / psychogenic non-epileptic seizures COGNIZANCE BIOMARKERS, INC. (US) 2025-12-16 US claimed
EP-0213326-A1 2,5-Dimethyl pyrrole derivatives, their preparation and their use CASSELLA Aktiengesellschaft (DE) 1987-03-11 EP claimed
EP-0205247-A2 Derivatives of quinuclidine STATE OF ISRAEL, REPRESENTED BY PRIME MINISTER'S OFFICE, ISRAEL INSTITUTE FOR BIOLOGICAL RESEARCH (IL) 1986-12-17 EP claimed
US-4620973-A PREVENTION OF SIDE EFFECTS OF ANTITUMOR AGENTS CIBA GEIGY CORPORATION (US) 1986-11-04 US claimed
EP-0050589-B1 PHARMACEUTICAL COMPOSITIONS WITH AN ANTI-EPILEPTIC AND ANTI-NEURALGIC EFFECT, AND PROCESS FOR THEIR MANUFACTURE CIBA-GEIGY AG (CH) 1984-09-12 EP claimed
EP-0116238-A1 Therapeutic compositions and their use in enhancing brain function BIOMEASURE, INC. (US) 1984-08-22 EP claimed
US-4431641-A AN ANTICONVULSANT DIBENZ/B,F/AZEPINE POTENTIATED BY A VINCAMINE OR PIRACETAM DERIVATIVE CIBA-GEIGY CORPORATION (US) 1984-02-14 US claimed
US-4385053-A ADMINISTERING LECITHIN AND PIRACETAM NEW YORK UNIVERSITY, A CORP. 1983-05-24 US claimed
US-4355027-A Process and composition for treating disorders by administering piracetam and choline MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 1982-10-19 US claimed
EP-0050589-A1 Pharmaceutical compositions with an anti-epileptic and anti-neuralgic effect, and process for their manufacture CIBA-GEIGY AG (CH) 1982-04-28 EP claimed
US-4115579-A 2-OXO-1-PYRROLIDINEACETAMIDE, 2-(2-OXOPYRROLIDINO)PROPIONAMIDE OR 2-(2-OXOPYRROLIDINO)BUTYRAMIDE U C B, SOCIETE ANONYME (BE) 1978-09-19 US claimed