Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 1.00 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | APEX1 | P27695 | 1/20 | 0.47 |
| ▸ | BLM | P54132 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | CA3 | P07451 | 1/20 | 0.44 |
| ▸ | CA4 | P22748 | 1/20 | 0.44 |
| ▸ | CA6 | P23280 | 1/20 | 0.44 |
| ▸ | CA5A | P35218 | 1/20 | 0.44 |
| ▸ | CA7 | P43166 | 1/20 | 0.44 |
| ▸ | CA9 | Q16790 | 1/20 | 0.44 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.44 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Piracetam SCHEMBL20172 | 1.00 | TSHR (1.00) | TSHRPIK3CDHTTKMT2ASMN1; SMN2 | |
| Piracetam SCHEMBL28423013 | 0.98 | TSHR (0.96) | TSHRPIK3CDHTTKMT2ASMN1; SMN2 | |
| SCHEMBL24263535 | 0.94 | TSHR (0.89) | TSHRPIK3CDHTTKMT2ASMN1; SMN2 | |
| SCHEMBL1532937 | 0.92 | TSHR (0.85) | TSHRPIK3CDHTTKMT2ASMN1; SMN2 | |
| SCHEMBL8552055 | 0.87 | — | — | |
| Piracetam SCHEMBL1756178 | 0.83 | TSHR (0.69) | TSHRHTTKMT2ASMN1; SMN2ALDH1A1 | |
| 4,4'-Methylenedianiline SCHEMBL20770172 | 0.83 | TSHR (0.69) | TSHRPIK3CDHTTKMT2ASMN1; SMN2 | |
| SCHEMBL22446137 | 0.82 | TSHR (0.69) | TSHRPIK3CDHTTKMT2ASMN1; SMN2 | |
| SCHEMBL948990 | 0.81 | TSHR (0.68) | TSHRPIK3CDHTTKMT2ASMN1; SMN2 | |
| SCHEMBL9628927 | 0.81 | TSHR (0.67) | TSHRPIK3CDHTTKMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017178682-A1 | COMPOSITIONS FOR THE PREVENTION AND/OR TREATMENT OF ALCOHOL USE DISORDERS | SERVICIO ANDALUZ DE SALUD (ES) | 2017-10-19 | — | — | WO | disclosed |
| CN-104435306-A | Application of blood-nourishing and brain-clearing preparation in preparation of medicament for treating Alzheimer disease | TASLY PHARMACEUTICAL GROUP CO | 2015-03-25 | — | — | CN | disclosed |
| EP-1498131-A1 | Medicinal preparation containing phenylethanoid glycosides extracted from Cistanche tubulosa | Sinphar Pharmaceutical Co., Ltd. (TW) | 2005-01-19 | — | — | EP | disclosed |