Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 3/20 | 0.63 |
| ▸ | RXRB | P28702 | 3/20 | 0.63 |
| ▸ | RXRG | P48443 | 2/20 | 0.63 |
| ▸ | HDAC1 | Q13547 | 7/20 | 0.58 |
| ▸ | HDAC2 | Q92769 | 6/20 | 0.58 |
| ▸ | HDAC6 | Q9UBN7 | 6/20 | 0.58 |
| ▸ | HDAC3 | O15379 | 5/20 | 0.58 |
| ▸ | HDAC4 | P56524 | 5/20 | 0.58 |
| ▸ | HDAC7 | Q8WUI4 | 5/20 | 0.58 |
| ▸ | HDAC10 | Q969S8 | 5/20 | 0.58 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.58 |
| ▸ | HDAC8 | Q9BY41 | 5/20 | 0.58 |
| ▸ | HDAC9 | Q9UKV0 | 5/20 | 0.58 |
| ▸ | HDAC5 | Q9UQL6 | 5/20 | 0.58 |
| ▸ | FAAH | O00519 | 6/20 | 0.57 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.47 |
| ▸ | CES1 | P23141 | 1/20 | 0.45 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.44 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.44 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3045891 | 0.86 | HDAC1 (0.76) | RXRARXRBRXRGHDAC1HDAC2 | |
| SCHEMBL4327548 | 0.86 | HDAC1 (0.76) | RXRARXRBRXRGHDAC1HDAC2 | |
| SCHEMBL4329559 | 0.85 | HDAC1 (0.77) | RXRARXRBRXRGHDAC1HDAC2 | |
| SCHEMBL10247700 | 0.83 | RXRA (0.78) | RXRARXRBRXRGHDAC1HDAC2 | |
| SCHEMBL416678 | 0.79 | HDAC1 (0.69) | RXRARXRBRXRGHDAC1HDAC2 | |
| SCHEMBL1474087 | 0.78 | FAAH (0.69) | RXRARXRBRXRGHDAC1HDAC2 | |
| SCHEMBL18169217 | 0.77 | RXRA (0.94) | RXRARXRBRXRGHDAC1HDAC2 | |
| SCHEMBL6069881 | 0.76 | RXRA (0.76) | RXRARXRBRXRGHDAC1HDAC2 | |
| SCHEMBL18169197 | 0.76 | RXRA (0.76) | RXRARXRBRXRGHDAC1HDAC2 | |
| SCHEMBL18169172 | 0.76 | RXRA (0.76) | RXRARXRBRXRGHDAC1HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0825989-A1 | SUBSTITUTED OXAZOLES FOR THE TREATMENT OF INFLAMMATION | G.D. SEARLE & CO. (US) | 1998-03-04 | — | — | EP | disclosed |