Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN1A | P35498 | 1/20 | 0.60 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.60 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | ADRB2 | P07550 | 3/20 | 0.49 |
| ▸ | MEN1 | O00255 | 3/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | DRD4 | P21917 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.46 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.46 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8554256 | 0.99 | SCN1A (0.59) | SCN1ASCN2ASCN3AKDM4EADRB2 | |
| SCHEMBL8551183 | 0.94 | SCN1A (0.68) | SCN1ASCN2ASCN3AKDM4EADRB2 | |
| Hydrochloric Acid SCHEMBL8553929 | 0.92 | SCN1A (0.66) | SCN1ASCN2ASCN3AKDM4EADRB2 | |
| SCHEMBL8551160 | 0.89 | SCN1A (0.61) | SCN1ASCN2ASCN3AKDM4EADRB2 | |
| SCHEMBL8553670 | 0.89 | SCN1A (0.61) | SCN1ASCN2ASCN3AKDM4EADRB2 | |
| Hydrochloric Acid SCHEMBL8554961 | 0.88 | SCN1A (0.60) | SCN1ASCN2ASCN3AKDM4EADRB2 | |
| SCHEMBL8553837 | 0.88 | SCN1A (0.60) | SCN1ASCN2ASCN3AKDM4EADRB2 | |
| Hydrochloric Acid SCHEMBL27561716 | 0.88 | SCN1A (0.60) | SCN1ASCN2ASCN3AKDM4EMEN1 | |
| SCHEMBL8550662 | 0.88 | SCN1A (0.63) | SCN1ASCN2ASCN3AMEN1KMT2A | |
| SCHEMBL8551383 | 0.88 | CARM1 (0.60) | SCN1ASCN2ASCN3AMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1084329-C | Benzyl piepridine derivs as pharmaceutical agents | HOFFMANN LA ROCHE (CH) | 2002-05-08 | — | — | CN | disclosed |
| EP-0871613-A1 | BENZYL PIPERIDINE DERIVATIVES AS PHARMACEUTICAL AGENTS | F. HOFFMANN-LA ROCHE AG (CH) | 1998-10-21 | — | — | EP | disclosed |
| CN-1183768-A | Benzyl piepridine derivs as pharmaceutical agents | HOFFMANN LA ROCHE (CH) | 1998-06-03 | — | — | CN | disclosed |
| US-5753679-A | SCIZOPHRENIA | HOFFMANN-LA ROCHE INC. (US) | 1998-05-19 | — | — | US | disclosed |
| WO-1996035666-A1 | BENZYL PIPERIDINE DERIVATIVES AS PHARMACEUTICAL AGENTS | F.HOFFMANN-LA ROCHE AG (CH) | 1996-11-14 | — | — | WO | disclosed |