Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 10/20 | 0.45 |
| ▸ | MAPT | P10636 | 9/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.45 |
| ▸ | MEN1 | O00255 | 6/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 6/20 | 0.45 |
| ▸ | HPGD | P15428 | 6/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.42 |
| ▸ | POLB | P06746 | 4/20 | 0.42 |
| ▸ | NPC1 | O15118 | 4/20 | 0.42 |
| ▸ | RAB9A | P51151 | 4/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | NR1I3 | Q14994 | 1/20 | 0.40 |
| ▸ | ESR1 | P03372 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8553318 | 0.86 | MAPT (0.43) | KMT2AMAPTALDH1A1MEN1NPSR1 | |
| SCHEMBL8550888 | 0.85 | KMT2A (0.44) | KMT2AMAPTALDH1A1MEN1NPSR1 | |
| SCHEMBL7145588 | 0.85 | MAPT (0.42) | KMT2AMAPTALDH1A1MEN1NPSR1 | |
| SCHEMBL8552436 | 0.77 | KMT2A (0.49) | KMT2AMAPTALDH1A1MEN1NPSR1 | |
| SCHEMBL7136637 | 0.71 | HTR1F (0.46) | KMT2AMAPTALDH1A1MEN1NPSR1 | |
| SCHEMBL24479782 | 0.62 | MAPT (0.71) | MAPTNPSR1HPGDSMN1; SMN2NPC1 | |
| SCHEMBL8548442 | 0.62 | HTR1F (0.48) | KMT2AMAPTALDH1A1MEN1SMN1; SMN2 | |
| SCHEMBL24479619 | 0.62 | MAPT (1.00) | KMT2AMAPTNPSR1HPGDSMN1; SMN2 | |
| SCHEMBL3863967 | 0.62 | NPC1 (0.55) | KMT2AMAPTALDH1A1MEN1NPSR1 | |
| SCHEMBL8549636 | 0.62 | HTR1F (0.51) | KMT2AMAPTALDH1A1MEN1NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0835869-A2 | New serotonin 5-HT1F agonists | ELI LILLY AND COMPANY (US) | 1998-04-15 | — | — | EP | disclosed |