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Phenyl Propionic Acid

Phenyl Propionic Acid

SCHEMBL8552444

CCCC(C)N1CCC(c2csc3ccc(NC(=O)Nc4cccc(C(C)=O)c4)cc23)CC1.O=C(O)CCc1ccccc1

nearest known ligand 0.46

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Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
▸ UBE2M P61081 20/20 0.46
▸ DCUN1D1 Q96GG9 20/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Phenyl Propionic Acid SCHEMBL8703826 0.94 UBE2M (0.47) UBE2MDCUN1D1
SCHEMBL8708863 0.87 UBE2M (0.47) UBE2MDCUN1D1
Phenyl Propionic Acid SCHEMBL7482914 0.86 HTR1D (0.46) UBE2MDCUN1D1
Phenyl Propionic Acid SCHEMBL8548350 0.86 UBE2M (0.46) UBE2MDCUN1D1
SCHEMBL8547528 0.83 UBE2M (0.49) UBE2MDCUN1D1
SCHEMBL8703840 0.82 UBE2M (0.44) UBE2MDCUN1D1
SCHEMBL8703829 0.79 UBE2M (0.47) UBE2MDCUN1D1
Phenyl Propionic Acid SCHEMBL8703758 0.79 UBE2M (0.47) UBE2MDCUN1D1
SCHEMBL8553038 0.77 UBE2M (0.42) UBE2MDCUN1D1
SCHEMBL8704365 0.76 DRD2 (0.42) UBE2MDCUN1D1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5792763-A MIGRAINES; ANALGESICS; DISEASES LINKED TO DECREASED NEUROTRANMISSION OF SEROTONIN IN MAMMALS ELI LILLY AND COMPANY (US) 1998-08-11 — — US disclosed
EP-0835869-A2 New serotonin 5-HT1F agonists ELI LILLY AND COMPANY (US) 1998-04-15 — — EP disclosed