Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B1 | P15538 | 4/20 | 0.43 |
| ▸ | CYP11B2 | P19099 | 4/20 | 0.43 |
| ▸ | PTAFR | P25105 | 4/20 | 0.40 |
| ▸ | CTSA | P10619 | 1/20 | 0.39 |
| ▸ | HPGDS | O60760 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.39 |
| ▸ | HTR1A | P08908 | 1/20 | 0.39 |
| ▸ | DRD2 | P14416 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | LRRK2 | Q5S007 | 2/20 | 0.38 |
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8477182 | 1.00 | CYP11B1 (0.43) | CYP11B1CYP11B2PTAFRCTSAHPGDS | |
| SCHEMBL8479518 | 0.86 | S1PR1 (0.45) | CYP11B1CYP11B2PTAFRNPC1RAB9A | |
| SCHEMBL8551234 | 0.86 | S1PR1 (0.45) | CYP11B1CYP11B2PTAFRNPC1RAB9A | |
| SCHEMBL8483096 | 0.85 | NAMPT (0.43) | CYP11B1CYP11B2PTAFRCYP17A1CYP3A4 | |
| SCHEMBL8551483 | 0.85 | NAMPT (0.43) | CYP11B1CYP11B2PTAFRCYP17A1CYP3A4 | |
| Oxalic Acid SCHEMBL8482061 | 0.83 | PDCD1 (0.45) | PTAFRNPC1RAB9ALRRK2EPHX1 | |
| SCHEMBL8480204 | 0.83 | LRRK2 (0.48) | CYP11B1CYP11B2PTAFRNPC1RAB9A | |
| SCHEMBL8109540 | 0.83 | MEN1 (0.52) | CYP11B1CYP11B2PTAFRNPC1RAB9A | |
| SCHEMBL8479732 | 0.83 | MEN1 (0.52) | CYP11B1CYP11B2PTAFRNPC1RAB9A | |
| SCHEMBL8481421 | 0.83 | MEN1 (0.52) | CYP11B1CYP11B2PTAFRNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0865431-A2 | COMPOUNDS | Astra Pharmaceuticals Limited (GB) | 1998-09-23 | — | — | EP | disclosed |
| WO-1997020815-A1 | COMPOUNDS | ASTRA PHARMACEUTICALS LTD. (GB) | 1997-06-12 | — | — | WO | disclosed |