Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 6/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.52 |
| ▸ | PKM | P14618 | 1/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9167070 | 0.83 | POLB (0.52) | HPGDALDH1A1L3MBTL1MAPTKDM4E | |
| SCHEMBL6942406 | 0.81 | HPGD (0.57) | HPGDHSD17B10ALDH1A1ALOX15MAPK1 | |
| SCHEMBL10839920 | 0.81 | HPGD (0.61) | HPGDHSD17B10ALDH1A1ALOX15MAPK1 | |
| SCHEMBL8625434 | 0.81 | HPGD (0.57) | HPGDHSD17B10ALDH1A1L3MBTL1PKM | |
| SCHEMBL8623561 | 0.80 | L3MBTL1 (0.72) | HPGDHSD17B10ALDH1A1ALOX15MAPK1 | |
| SCHEMBL6748722 | 0.78 | MAPT (0.61) | HPGDALDH1A1MAPK1L3MBTL1MAPT | |
| SCHEMBL24532106 | 0.78 | HPGD (0.47) | HPGDHSD17B10ALDH1A1ALOX15MAPK1 | |
| SCHEMBL11094447 | 0.77 | MAPT (0.47) | HPGDALDH1A1L3MBTL1MAPTKDM4E | |
| SCHEMBL13669850 | 0.76 | MAPT (0.51) | HSD17B10ALDH1A1L3MBTL1MAPTKDM4E | |
| SCHEMBL4436794 | 0.75 | HSD17B10 (0.54) | HPGDHSD17B10ALDH1A1ALOX15MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0846112-A1 | BICYCLIC HERBICIDES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1998-06-10 | — | — | EP | disclosed |
| WO-1997008164-A1 | BICYCLIC HERBICIDES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1997-03-06 | — | — | WO | disclosed |