SCHEMBL8552859

SCHEMBL8552859

CCCCCC(=O)N1CCC[N]CC1

nearest known ligand 0.71

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 2/20 0.71
MEN1 O00255 2/20 0.69
KMT2A Q03164 2/20 0.69
TDP1 Q9NUW8 1/20 0.69
GNAI3 P08754 9/20 0.53
GNAI1 P63096 9/20 0.53
GNAO1 P09471 8/20 0.50
ATM Q13315 1/20 0.50
POLB P06746 2/20 0.46
MAPT P10636 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8557820 0.95 L3MBTL1 (0.62) L3MBTL1MEN1KMT2ATDP1GNAI3
SCHEMBL7506937 0.93 L3MBTL1 (0.69) L3MBTL1MEN1KMT2ATDP1GNAI3
SCHEMBL6536785 0.91 L3MBTL1 (0.67) L3MBTL1MEN1KMT2ATDP1GNAI3
SCHEMBL8557452 0.88 L3MBTL1 (0.52) L3MBTL1MEN1KMT2ATDP1GNAI3
SCHEMBL4684014 0.88 L3MBTL1 (0.60) L3MBTL1MEN1KMT2ATDP1GNAI3
SCHEMBL6466560 0.84 L3MBTL1 (1.00) L3MBTL1MEN1KMT2ATDP1GNAI3
SCHEMBL9761341 0.84 L3MBTL1 (0.92) L3MBTL1MEN1KMT2ATDP1GNAI3
SCHEMBL1579948 0.83 ATM (0.50) L3MBTL1MEN1KMT2ATDP1GNAI3
SCHEMBL10494122 0.82 L3MBTL1 (0.96) L3MBTL1MEN1KMT2ATDP1GNAI3
SCHEMBL10290341 0.82 L3MBTL1 (0.96) L3MBTL1MEN1KMT2ATDP1GNAI3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5811576-A 1-CARBOXY-2-LOWERALKYL-3,4,6-TRI(HALO)BENZENES; GRAMPOSITIVE AND-NEGATIVE BACTERIA; INFECTIONS; STERILIZATION OF MEDICAL EQUIPMENT OTSUKA PHARMACEUTICAL COMPANY, LIMITED (JP) 1998-09-22 US disclosed
US-5723648-A Intermediates for anti-microbial benzoheterocyclic compounds OTSUKA PHARMACEUTICAL COMPANY, LIMITED (JP) 1998-03-03 US disclosed
EP-0823413-A2 Benzoheterocyclic compounds OTSUKA PHARMACEUTICAL CO., LTD. (JP) 1998-02-11 EP disclosed
US-5591744-A 1,4-DIHYDRO-4-OXOQUINOLINE-3-CARBOXYLATE DERIVATIVES; MICROBIOCIDES OTSUKA PHARMACEUTICAL COMPANY, LIMITED (JP) 1997-01-07 US disclosed
US-5563138-A 4-OXOQUINOLINE-3-CARBOXYLIC ACID COMPOUNDS HAVING ANTIMICROBIAL ACTIVITY OTSUKA PHARMACEUTICAL COMPANY, LIMITED (JP) 1996-10-08 US disclosed
US-5495020-A CHEMICAL INTERMEDIATE FOR BACTERICIDES, MICROBIOCIDES, DISINFECTANTS; SIDE EFFECT REDUCTION, ABSORPTION OTSUKA PHARMACEUTICAL COMPANY, LIMITED (JP) 1996-02-27 US disclosed
US-5290934-A Benzoheterocyclic compounds OTSUKA PHARMACEUTICAL COMPANY, LIMITED (JP) 1994-03-01 US disclosed
EP-0565132-A2 Benzoheterocyclic compounds OTSUKA PHARMACEUTICAL CO., LTD. (JP) 1993-10-13 EP disclosed
EP-0287951-A2 7-Piperazinyl- or 7-Morpholino-4-oxo-quinoline-3-carboxylic acid derivatives, their preparation and their use as antimicrobial agents OTSUKA PHARMACEUTICAL CO., LTD. (JP) 1988-10-26 EP disclosed