SCHEMBL9761341

SCHEMBL9761341

CCCCCC(=O)N1CCC1

nearest known ligand 0.92

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 2/20 0.92
MEN1 O00255 2/20 0.88
KMT2A Q03164 2/20 0.88
TDP1 Q9NUW8 1/20 0.88
GNAI3 P08754 9/20 0.65
GNAI1 P63096 9/20 0.65
ATM Q13315 1/20 0.64
GNAO1 P09471 8/20 0.61
POLB P06746 2/20 0.56
MAPT P10636 1/20 0.56
NPC1 O15118 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9762648 0.98 L3MBTL1 (0.88) L3MBTL1MEN1KMT2ATDP1GNAI3
SCHEMBL13290614 0.96 L3MBTL1 (0.85) L3MBTL1MEN1KMT2ATDP1GNAI3
SCHEMBL6466560 0.96 L3MBTL1 (1.00) L3MBTL1MEN1KMT2ATDP1GNAI3
SCHEMBL10534171 0.94 L3MBTL1 (0.96) L3MBTL1MEN1KMT2ATDP1GNAI3
SCHEMBL10535931 0.94 L3MBTL1 (1.00) L3MBTL1MEN1KMT2ATDP1GNAI3
SCHEMBL1492484 0.94 L3MBTL1 (1.00) L3MBTL1MEN1KMT2ATDP1GNAI3
SCHEMBL10494122 0.94 L3MBTL1 (0.96) L3MBTL1MEN1KMT2ATDP1GNAI3
SCHEMBL249052 0.94 L3MBTL1 (0.96) L3MBTL1MEN1KMT2ATDP1GNAI3
N-(Decanoyl)Pyrrolidine SCHEMBL10755236 0.94 L3MBTL1 (0.96) L3MBTL1MEN1KMT2ATDP1GNAI3
SCHEMBL10290341 0.94 L3MBTL1 (0.96) L3MBTL1MEN1KMT2ATDP1GNAI3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023144160-A1 NEW HETEROCYCLIC COMPOUNDS F. HOFFMANN-LA ROCHE AG (CH) 2023-08-03 WO claimed
WO-2023144160-A1 NEW HETEROCYCLIC COMPOUNDS F. HOFFMANN-LA ROCHE AG (CH) 2023-08-03 WO disclosed
US-5045432-A Negative working lithography printing plates EASTMAN KODAK COMPANY (US) 1991-09-03 US disclosed
US-5043250-A Negative working; shelf life, image contrast EASTMAN KODAK COMPANY (US) 1991-08-27 US disclosed