Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMYD3 | Q9H7B4 | 7/20 | 0.43 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.37 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.37 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.37 |
| ▸ | KDM1A | O60341 | 2/20 | 0.36 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.36 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | ITGB3 | P05106 | 3/20 | 0.34 |
| ▸ | ITGA2B | P08514 | 3/20 | 0.34 |
| ▸ | UTS2R | Q9UKP6 | 1/20 | 0.34 |
| ▸ | HPGDS | O60760 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8552049 | 0.89 | SMYD3 (0.43) | SMYD3ALDH1A1TSHRUTS2RHPGDS | |
| Hydrochloric Acid SCHEMBL8592818 | 0.88 | SMYD3 (0.41) | SMYD3CARM1PRMT6UTS2R | |
| SCHEMBL8550362 | 0.83 | SMYD3 (0.40) | SMYD3ALDH1A1TSHRITGB3ITGA2B | |
| SCHEMBL8550368 | 0.83 | SMYD3 (0.40) | SMYD3ALDH1A1TSHRITGB3ITGA2B | |
| Hydrochloric Acid SCHEMBL8551138 | 0.82 | SMYD3 (0.40) | SMYD3ALDH1A1TSHRITGB3ITGA2B | |
| SCHEMBL8549842 | 0.81 | SMYD3 (0.41) | SMYD3ADRA1DADRA1AADRA1BKDM1A | |
| Hydrochloric Acid SCHEMBL8551719 | 0.81 | SMYD3 (0.42) | SMYD3ALDH1A1UTS2R | |
| SCHEMBL8555209 | 0.79 | KDM4E (0.36) | SMYD3TSHR | |
| SCHEMBL8551904 | 0.77 | ALDH1A1 (0.51) | ALDH1A1TSHR | |
| Hydrochloric Acid SCHEMBL8592586 | 0.77 | SMYD3 (0.37) | SMYD3ALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0858457-A1 | 5-MEMBERED HETEROCYCLES, PHARMACEUTICAL AGENTS CONTAINING SAID COMPOUNDS AND THE USE THEREOF AND METHODS OF PRODUCING THEM | Dr. Karl Thomae GmbH (DE) | 1998-08-19 | — | — | EP | disclosed |
| WO-1997015567-A1 | 5-MEMBERED HETEROCYCLES, PHARMACEUTICAL AGENTS CONTAINING SAID COMPOUNDS AND THE USE THEREOF AND METHODS OF PRODUCING THEM | DR. KARL THOMAE GMBH (DE) | 1997-05-01 | — | — | WO | disclosed |