Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 6/20 | 0.40 |
| ▸ | NPC1 | O15118 | 5/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | DGAT2 | Q96PD7 | 1/20 | 0.37 |
| ▸ | MAOB | P27338 | 2/20 | 0.34 |
| ▸ | MAOA | P21397 | 1/20 | 0.34 |
| ▸ | ESR1 | P03372 | 1/20 | 0.32 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.32 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8550273 | 0.90 | RAB9A (0.42) | RAB9ANPC1SMN1; SMN2POLBTDP1 | |
| SCHEMBL8552889 | 0.90 | RAB9A (0.42) | RAB9ANPC1SMN1; SMN2POLBTDP1 | |
| SCHEMBL8552242 | 0.89 | RAB9A (0.42) | RAB9ANPC1SMN1; SMN2POLBTDP1 | |
| SCHEMBL8553401 | 0.88 | RAB9A (0.41) | RAB9ANPC1SMN1; SMN2POLBTDP1 | |
| SCHEMBL8553406 | 0.87 | RAB9A (0.40) | RAB9ANPC1SMN1; SMN2POLBTDP1 | |
| SCHEMBL8551414 | 0.84 | RAB9A (0.42) | RAB9ANPC1SMN1; SMN2POLBTDP1 | |
| SCHEMBL8556024 | 0.82 | RAB9A (0.44) | RAB9ANPC1SMN1; SMN2POLBTDP1 | |
| SCHEMBL8552782 | 0.81 | ADAMTS5 (0.43) | RAB9ANPC1SMN1; SMN2POLBTDP1 | |
| SCHEMBL8551098 | 0.81 | RAB9A (0.45) | RAB9ANPC1SMN1; SMN2POLBTDP1 | |
| SCHEMBL8552015 | 0.79 | RAB9A (0.43) | RAB9ANPC1SMN1; SMN2POLBTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0871442-A1 | BENZIMIDZOLYL NEUROPEPTIDE Y RECEPTOR ANTAGONISTS | ELI LILLY AND COMPANY (US) | 1998-10-21 | — | — | EP | disclosed |
| WO-1997025041-A1 | BENZIMIDZOLYL NEUROPEPTIDE Y RECEPTOR ANTAGONISTS | ELI LILLY AND COMPANY (US) | 1997-07-17 | — | — | WO | disclosed |