Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 4/20 | 0.49 |
| ▸ | CA1 | P00915 | 3/20 | 0.49 |
| ▸ | FAAH | O00519 | 4/20 | 0.36 |
| ▸ | CES1 | P23141 | 3/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | FKBP1A | P62942 | 2/20 | 0.35 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.35 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.35 |
| ▸ | MGLL | Q99685 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8555026 | 0.94 | CA2 (0.44) | CA2CA1 | |
| SCHEMBL27525477 | 0.91 | CA2 (0.54) | CA2CA1FAAHCES1FFAR1 | |
| SCHEMBL8551008 | 0.89 | CA2 (0.48) | CA2CA1FAAHCES1TDP1 | |
| SCHEMBL8811229 | 0.88 | CA2 (0.48) | CA2CA1FAAHCES1TDP1 | |
| SCHEMBL23291910 | 0.82 | CA2 (0.69) | CA2CA1FFAR1 | |
| SCHEMBL8300371 | 0.80 | CA2 (0.41) | CA2CA1FAAHCES1FFAR1 | |
| SCHEMBL8722410 | 0.80 | TAAR1 (0.46) | TDP1L3MBTL1 | |
| SCHEMBL11669981 | 0.80 | TAAR1 (0.46) | TDP1L3MBTL1 | |
| SCHEMBL8441263 | 0.79 | CA2 (0.53) | CA2CA1FAAHCES1FFAR1 | |
| SCHEMBL8077441 | 0.79 | CA2 (0.53) | CA2CA1FAAHCES1FFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0840725-A1 | AZETIDINONE DERIVATIVES FOR THE TREATMENT OF ATHEROSCLEROSIS | SMITHKLINE BEECHAM PLC (GB) | 1998-05-13 | — | — | EP | disclosed |
| WO-1997002242-A1 | AZETIDINONE DERIVATIVES FOR THE TREATMENT OF ATHEROSCLEROSIS | SMITHKLINE BEECHAM PLC (GB) | 1997-01-23 | — | — | WO | disclosed |