Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 3/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.54 |
| ▸ | MAPT | P10636 | 3/20 | 0.54 |
| ▸ | BRPF1 | P55201 | 4/20 | 0.52 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.48 |
| ▸ | BRD4 | O60885 | 1/20 | 0.48 |
| ▸ | KCNK3 | O14649 | 4/20 | 0.47 |
| ▸ | KCNK9 | Q9NPC2 | 4/20 | 0.47 |
| ▸ | GAA | P10253 | 3/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | HTR2A | P28223 | 1/20 | 0.45 |
| ▸ | TSPO | P30536 | 1/20 | 0.45 |
| ▸ | GPR183 | P32249 | 1/20 | 0.45 |
| ▸ | APLNR | P35414 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8549283 | 0.80 | MAPT (0.56) | RAB9ASMN1; SMN2MAPTRXFP1GAA | |
| SCHEMBL261957 | 0.77 | MAPT (0.49) | RAB9ASMN1; SMN2MAPTGAANPC1 | |
| SCHEMBL15528489 | 0.74 | TSHR (0.74) | MAPTBRPF1RXFP1KCNK3KCNK9 | |
| SCHEMBL846695 | 0.73 | TRPV1 (0.58) | RAB9ASMN1; SMN2MAPTKCNK9NPC1 | |
| SCHEMBL15945345 | 0.73 | MAPT (0.55) | RAB9ASMN1; SMN2MAPTNPC1ALDH1A1 | |
| SCHEMBL6964824 | 0.71 | ALDH1A1 (0.51) | RAB9ASMN1; SMN2MAPTGAANPC1 | |
| SCHEMBL11374287 | 0.71 | GAA (0.56) | MAPTBRPF1RXFP1KCNK3KCNK9 | |
| SCHEMBL6966994 | 0.70 | KMT2A (0.55) | SMN1; SMN2MAPTGAAALDH1A1KMT2A | |
| SCHEMBL6956521 | 0.70 | MAPT (0.42) | RAB9ASMN1; SMN2MAPTGAANPC1 | |
| SCHEMBL2040491 | 0.70 | ALDH1A1 (0.59) | RAB9ASMN1; SMN2MAPTGAAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0850222-A1 | PIPERAZINE DERIVATIVES AND PROCESS FOR THE PREPARATION THEREOF | Samjin Pharmaceutical Co., Ltd. (KR) | 1998-07-01 | — | — | EP | disclosed |
| WO-1998000402-A1 | PIPERAZINE DERIVATIVES AND PROCESS FOR THE PREPARATION THEREOF | SAMJIN PHARMACEUTICAL CO., LTD. (KR) | 1998-01-08 | — | — | WO | disclosed |