Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RET | P07949 | 3/20 | 0.34 |
| ▸ | DAPK3 | O43293 | 2/20 | 0.34 |
| ▸ | PRKD3 | O94806 | 2/20 | 0.34 |
| ▸ | MAP4K4 | O95819 | 2/20 | 0.34 |
| ▸ | CSF1R | P07333 | 2/20 | 0.34 |
| ▸ | FGFR1 | P11362 | 2/20 | 0.34 |
| ▸ | FLT1 | P17948 | 2/20 | 0.34 |
| ▸ | LTK | P29376 | 2/20 | 0.34 |
| ▸ | KDR | P35968 | 2/20 | 0.34 |
| ▸ | CSNK1A1 | P48729 | 2/20 | 0.34 |
| ▸ | CDK7 | P50613 | 2/20 | 0.34 |
| ▸ | RPS6KA3 | P51812 | 2/20 | 0.34 |
| ▸ | CDK5 | Q00535 | 2/20 | 0.34 |
| ▸ | TYRO3 | Q06418 | 2/20 | 0.34 |
| ▸ | CLK4 | Q9HAZ1 | 2/20 | 0.34 |
| ▸ | ALK | Q9UM73 | 2/20 | 0.34 |
| ▸ | DYRK1B | Q9Y463 | 2/20 | 0.34 |
| ▸ | PAK4 | O96013 | 1/20 | 0.34 |
| ▸ | ABL1 | P00519 | 1/20 | 0.34 |
| ▸ | LCK | P06239 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1815177 | 0.61 | — | — | |
| SCHEMBL8553212 | 0.60 | PNP (0.41) | LMNA | |
| SCHEMBL14793616 | 0.59 | DAPK3 (0.30) | RETDAPK3PRKD3MAP4K4CSF1R | |
| SCHEMBL2255360 | 0.59 | DAPK3 (0.30) | RETDAPK3PRKD3MAP4K4CSF1R | |
| SCHEMBL2254848 | 0.59 | DAPK3 (0.33) | RETDAPK3PRKD3MAP4K4CSF1R | |
| SCHEMBL9575197 | 0.58 | CCR4 (0.39) | RETDAPK3PRKD3MAP4K4CSF1R | |
| SCHEMBL3354788 | 0.57 | LRRK2 (0.31) | RETDAPK3PRKD3MAP4K4CSF1R | |
| SCHEMBL536971 | 0.57 | LRRK2 (0.31) | RETDAPK3PRKD3MAP4K4CSF1R | |
| SCHEMBL2440226 | 0.57 | CYP1A2 (0.33) | GSK3B | |
| SCHEMBL8918021 | 0.57 | PI4KA (0.31) | RETLRRK2PI4KAXDHPI4K2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0719265-B1 | NUCLEOSIDE DERIVATIVES, METHODS FOR THE MANUFACTURE THEREOF AND SPECIFIC POLYCLONAL AND MONOCLONAL ANTIBODIES OF SAID DERIVATIVES | COMMISSARIAT ENERGIE ATOMIQUE (FR) | 1998-12-02 | — | — | EP | claimed |
| US-5721341-A | Derivatives of nucleosides, processes for the production of these derivatives of nucleosides and specific polyclonal and monoclonal antibodies of these derivatives | COMMISSARIAT A L'ENERGIE ATOMIQUE (FR) | 1998-02-24 | — | — | US | claimed |