Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR4 | P51679 | 1/20 | 0.39 |
| ▸ | RET | P07949 | 4/20 | 0.36 |
| ▸ | LRRK2 | Q5S007 | 3/20 | 0.36 |
| ▸ | PI4KA | P42356 | 3/20 | 0.36 |
| ▸ | PI4K2B | Q8TCG2 | 3/20 | 0.36 |
| ▸ | PI4K2A | Q9BTU6 | 3/20 | 0.36 |
| ▸ | PI4KB | Q9UBF8 | 3/20 | 0.36 |
| ▸ | XDH | P47989 | 2/20 | 0.36 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | LIMK1 | P53667 | 3/20 | 0.35 |
| ▸ | DAPK3 | O43293 | 3/20 | 0.35 |
| ▸ | PRKD3 | O94806 | 3/20 | 0.35 |
| ▸ | MAP4K4 | O95819 | 3/20 | 0.35 |
| ▸ | KDR | P35968 | 3/20 | 0.35 |
| ▸ | CSNK1A1 | P48729 | 3/20 | 0.35 |
| ▸ | RPS6KA3 | P51812 | 3/20 | 0.35 |
| ▸ | CDK5 | Q00535 | 3/20 | 0.35 |
| ▸ | CLK4 | Q9HAZ1 | 3/20 | 0.35 |
| ▸ | AURKB | Q96GD4 | 3/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18897049 | 0.67 | ALDH1A1 (0.50) | ALDH1A1KDRAURKBCHEK1PIM1 | |
| SCHEMBL28508442 | 0.64 | RET (0.43) | RETLRRK2PI4KAPI4K2BPI4K2A | |
| SCHEMBL21362197 | 0.63 | ATG7 (0.39) | RETLRRK2PI4KAPI4K2BPI4K2A | |
| SCHEMBL21362233 | 0.63 | DYRK1A (0.43) | RETLRRK2PI4KAPI4K2BPI4K2A | |
| SCHEMBL14736182 | 0.63 | CHEK1 (0.51) | RETLRRK2PI4KAPI4K2BPI4K2A | |
| SCHEMBL18152242 | 0.63 | AURKA (0.41) | RETLRRK2LIMK1DAPK3MAP4K4 | |
| SCHEMBL5805420 | 0.62 | RET (0.43) | RETLRRK2PI4KAPI4K2BPI4K2A | |
| SCHEMBL48258 | 0.61 | ERAP1 (0.61) | RETLRRK2PI4KAPI4K2BPI4K2A | |
| SCHEMBL14647390 | 0.61 | RET (0.41) | RETLRRK2PI4KAPI4K2BPI4K2A | |
| SCHEMBL6531144 | 0.61 | RET (0.42) | RETLRRK2PI4KAPI4K2BPI4K2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-5310742-A | — | — | None | — | — | JP | disclosed |
| JP-2016968-A | — | — | None | — | — | JP | disclosed |
| JP-H05310742-A | NEW SUBSTANCE ACARON AND ITS USE | KAIYO BIO TECHNOL KENKYUSHO:KK | 1993-11-22 | — | — | JP | disclosed |
| JP-H0216968-A | RIBOFLAVIN-OVERPRODUCING STRAIN | ADOLPH COORS CO | 1990-01-19 | — | — | JP | disclosed |