Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | IL2 | P60568 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 2/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.32 |
| ▸ | FABP4 | P15090 | 1/20 | 0.31 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8630585 | 0.76 | KDM4E (0.47) | KDM4EHTTLMNAMAPTIL2 | |
| SCHEMBL610883 | 0.73 | HTT (0.47) | KDM4EHTTLMNAMAPTIL2 | |
| SCHEMBL2886677 | 0.73 | KDM4E (0.59) | KDM4EHTTLMNAMAPTIL2 | |
| SCHEMBL9085324 | 0.73 | KDM4E (0.42) | KDM4EHTTLMNAMAPTIL2 | |
| SCHEMBL2886094 | 0.72 | KDM4E (0.53) | KDM4EHTTLMNAMAPTIL2 | |
| SCHEMBL9088744 | 0.72 | HTT (0.43) | KDM4EHTTLMNAMAPTIL2 | |
| SCHEMBL610146 | 0.72 | LMNA (0.43) | KDM4EHTTLMNAMAPTIL2 | |
| SCHEMBL9089557 | 0.70 | KDM4E (0.42) | KDM4EHTTLMNAMAPTIL2 | |
| SCHEMBL5778345 | 0.69 | LMNA (0.43) | KDM4EHTTLMNAMAPTIL2 | |
| SCHEMBL9791116 | 0.68 | KDM4E (0.44) | KDM4EHTTLMNAMAPTIL2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0816362-A1 | THIAZOLE DERIVATIVES | TAISHO PHARMACEUTICAL CO. LTD (JP) | 1998-01-07 | — | — | EP | disclosed |