Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESRRG | P62508 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | BLM | P54132 | 1/20 | 0.34 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.33 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.33 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.33 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.33 |
| ▸ | MIF | P14174 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | ESRRB | O95718 | 2/20 | 0.32 |
| ▸ | F13A1 | P00488 | 1/20 | 0.32 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.32 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.32 |
| ▸ | CTSS | P25774 | 1/20 | 0.32 |
| ▸ | CTSK | P43235 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20487133 | 0.88 | MAPT (0.35) | — | |
| SCHEMBL17894517 | 0.88 | GRM2 (0.38) | BLMGRM2MIFCA2L3MBTL1 | |
| SCHEMBL2164170 | 0.85 | S1PR1 (0.41) | CA2L3MBTL1 | |
| SCHEMBL7473461 | 0.82 | ESRRG (0.44) | ESRRGKDM4EBLMGRM2OPRM1 | |
| SCHEMBL206993 | 0.81 | ACHE (0.34) | GRM2L3MBTL1NR1H2NR1H3CTSK | |
| SCHEMBL16216171 | 0.79 | GRM2 (0.41) | GRM2NR1H2NR1H3 | |
| SCHEMBL20852483 | 0.79 | GRM2 (0.41) | GRM2NR1H2NR1H3 | |
| SCHEMBL16208901 | 0.78 | PSMD10 (0.35) | CA2 | |
| SCHEMBL3488741 | 0.78 | L3MBTL1 (0.52) | L3MBTL1CTSS | |
| SCHEMBL5834977 | 0.78 | GRM2 (0.38) | KDM4EGRM2NR1H2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0869949-A1 | BENZOXAZINE ANTIMICROBIAL AGENTS | ORTHO PHARMACEUTICAL CORPORATION (US) | 1998-10-14 | — | — | EP | disclosed |
| WO-1997017333-A1 | BENZOXAZINE ANTIMICROBIAL AGENTS | ORTHO PHARMACEUTICAL CORPORATION (US) | 1997-05-15 | — | — | WO | disclosed |