Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | GRM2 | Q14416 | 14/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8552354 | 0.88 | GRM2 (0.42) | HPGDGRM2TSHR | |
| SCHEMBL8554255 | 0.86 | MAOA (0.44) | HPGD | |
| SCHEMBL6399467 | 0.79 | GRM2 (0.40) | HPGDGRM2 | |
| SCHEMBL6399463 | 0.79 | GRM2 (0.40) | HPGDGRM2 | |
| SCHEMBL8557287 | 0.76 | MAOA (0.41) | GRM2 | |
| SCHEMBL8799672 | 0.75 | GRM2 (0.60) | GRM2 | |
| SCHEMBL7545023 | 0.75 | GRM2 (0.60) | GRM2 | |
| SCHEMBL9085710 | 0.75 | GRM2 (0.60) | GRM2 | |
| SCHEMBL7127112 | 0.74 | MAOA (0.48) | — | |
| SCHEMBL8799676 | 0.74 | GRM2 (0.65) | GRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0856002-A1 | PHENYLOXAZOLIDINONES HAVING A C-C BOND TO 4-8 MEMBERED HETEROCYCLIC RINGS | PHARMACIA & UPJOHN COMPANY (US) | 1998-08-05 | — | — | EP | disclosed |
| WO-1997009328-A1 | PHENYLOXAZOLIDINONES HAVING A C-C BOND TO 4-8 MEMBERED HETEROCYCLIC RINGS | PHARMACIA & UPJOHN COMPANY (US) | 1997-03-13 | — | — | WO | disclosed |