Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM2 | Q14416 | 4/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | CALML3 | P27482 | 4/20 | 0.41 |
| ▸ | MAOA | P21397 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | F10 | P00742 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8554255 | 0.89 | MAOA (0.44) | HPGDCALML3MAOAMAOBF10 | |
| SCHEMBL8553161 | 0.88 | HPGD (0.40) | GRM2HPGDTSHR | |
| SCHEMBL7127112 | 0.77 | MAOA (0.48) | CALML3MAOAMAOBF10 | |
| SCHEMBL6396892 | 0.77 | GRM2 (0.43) | GRM2HPGDCALML3MAOAMAOB | |
| SCHEMBL6396899 | 0.77 | GRM2 (0.43) | GRM2HPGDCALML3MAOAMAOB | |
| SCHEMBL8553013 | 0.75 | MAOA (0.46) | CALML3MAOAMAOBF10 | |
| SCHEMBL8551980 | 0.73 | CALML3 (0.53) | CALML3MAOAMAOB | |
| SCHEMBL8549873 | 0.73 | ROCK2 (0.51) | MAOAMAOBTSHR | |
| SCHEMBL8027128 | 0.73 | MAOA (0.48) | CALML3MAOAMAOBF10 | |
| SCHEMBL8553593 | 0.73 | MAOA (0.46) | CALML3MAOAMAOBF10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0856002-A1 | PHENYLOXAZOLIDINONES HAVING A C-C BOND TO 4-8 MEMBERED HETEROCYCLIC RINGS | PHARMACIA & UPJOHN COMPANY (US) | 1998-08-05 | — | — | EP | disclosed |
| WO-1997009328-A1 | PHENYLOXAZOLIDINONES HAVING A C-C BOND TO 4-8 MEMBERED HETEROCYCLIC RINGS | PHARMACIA & UPJOHN COMPANY (US) | 1997-03-13 | — | — | WO | disclosed |