Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.67 |
| ▸ | SLC5A1 | P13866 | 1/20 | 0.51 |
| ▸ | SLC5A2 | P31639 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 5/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.47 |
| ▸ | MAPT | P10636 | 5/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.41 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | BRD4 | O60885 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8557086 | 0.91 | TSHR (0.67) | TSHRSLC5A1SLC5A2MEN1KMT2A | |
| SCHEMBL31490076 | 0.86 | SLC5A1 (0.54) | TSHRSLC5A1SLC5A2MEN1KMT2A | |
| SCHEMBL10048208 | 0.83 | SLC5A1 (0.65) | SLC5A1SLC5A2MEN1KMT2AL3MBTL1 | |
| SCHEMBL10374449 | 0.81 | SLC5A1 (0.50) | TSHRSLC5A1SLC5A2MEN1KMT2A | |
| SCHEMBL10374403 | 0.78 | SLC5A1 (0.48) | TSHRSLC5A1SLC5A2MEN1KMT2A | |
| SCHEMBL8878727 | 0.78 | SLC5A1 (0.46) | TSHRSLC5A1SLC5A2MEN1KMT2A | |
| SCHEMBL30806430 | 0.77 | CYP1A2 (0.56) | TSHRMEN1KMT2AMAPTCYP1A2 | |
| SCHEMBL27376612 | 0.77 | CYP1A2 (0.56) | TSHRMEN1KMT2AMAPTCYP1A2 | |
| SCHEMBL4118904 | 0.77 | KCNH2 (0.48) | SLC5A1SLC5A2MEN1KMT2AMAPT | |
| SCHEMBL27376595 | 0.77 | CASP1 (0.56) | TSHRSLC5A1SLC5A2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0869949-A1 | BENZOXAZINE ANTIMICROBIAL AGENTS | ORTHO PHARMACEUTICAL CORPORATION (US) | 1998-10-14 | — | — | EP | disclosed |
| WO-1997017333-A1 | BENZOXAZINE ANTIMICROBIAL AGENTS | ORTHO PHARMACEUTICAL CORPORATION (US) | 1997-05-15 | — | — | WO | disclosed |