Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.67 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | SLC5A1 | P13866 | 1/20 | 0.45 |
| ▸ | SLC5A2 | P31639 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 4/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | CASP1 | P29466 | 1/20 | 0.41 |
| ▸ | CASP3 | P42574 | 1/20 | 0.41 |
| ▸ | CASP4 | P49662 | 1/20 | 0.41 |
| ▸ | CASP7 | P55210 | 1/20 | 0.41 |
| ▸ | CASP9 | P55211 | 1/20 | 0.41 |
| ▸ | CASP6 | P55212 | 1/20 | 0.41 |
| ▸ | CASP8 | Q14790 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8553215 | 0.91 | TSHR (0.67) | TSHRCYP1A2CYP2C19CYP2C9SLC5A1 | |
| SCHEMBL27376595 | 0.86 | CASP1 (0.56) | TSHRCYP2C19CYP2C9SLC5A1SLC5A2 | |
| SCHEMBL8624433 | 0.83 | SLC5A1 (0.51) | TSHRSLC5A1SLC5A2CASP1CASP3 | |
| SCHEMBL29256246 | 0.83 | TSHR (0.45) | TSHRSLC5A1SLC5A2MEN1KMT2A | |
| SCHEMBL27377925 | 0.81 | SLC5A1 (0.48) | TSHRCYP1A2CYP2C19CYP2C9SLC5A1 | |
| SCHEMBL27376612 | 0.80 | CYP1A2 (0.56) | TSHRCYP1A2CYP2C19CYP2C9CYP2D6 | |
| SCHEMBL30806430 | 0.80 | CYP1A2 (0.56) | TSHRCYP1A2CYP2C19CYP2C9CYP2D6 | |
| SCHEMBL9687134 | 0.79 | BRD4 (0.50) | TSHRSLC5A1SLC5A2MEN1KMT2A | |
| SCHEMBL282621 | 0.79 | TERT (0.44) | SLC5A1SLC5A2MEN1KMT2AGAA | |
| SCHEMBL8130592 | 0.78 | TERT (0.48) | TSHRCYP1A2SLC5A1SLC5A2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0869949-A1 | BENZOXAZINE ANTIMICROBIAL AGENTS | ORTHO PHARMACEUTICAL CORPORATION (US) | 1998-10-14 | — | — | EP | disclosed |
| WO-1997017333-A1 | BENZOXAZINE ANTIMICROBIAL AGENTS | ORTHO PHARMACEUTICAL CORPORATION (US) | 1997-05-15 | — | — | WO | disclosed |