Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 8/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.41 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8552315 | 0.93 | TSHR (0.43) | PPARGALDH1A1SMN1; SMN2TSHRTP53 | |
| SCHEMBL8554869 | 0.93 | TP53 (0.45) | PPARGALDH1A1SMN1; SMN2TSHRTP53 | |
| SCHEMBL8555357 | 0.92 | PPARG (0.46) | PPARGALDH1A1SMN1; SMN2TSHRTP53 | |
| SCHEMBL8644730 | 0.92 | PPARG (0.47) | PPARGALDH1A1SMN1; SMN2TSHRTP53 | |
| SCHEMBL8554119 | 0.90 | TSHR (0.43) | PPARGALDH1A1SMN1; SMN2TSHRTP53 | |
| SCHEMBL8603793 | 0.88 | ALDH1A1 (0.45) | PPARGALDH1A1SMN1; SMN2TSHRTP53 | |
| SCHEMBL8555175 | 0.85 | FAAH (0.50) | PPARGALDH1A1SMN1; SMN2TSHRTP53 | |
| SCHEMBL8665582 | 0.84 | PPARG (0.45) | PPARGALDH1A1TSHRTP53 | |
| SCHEMBL8555379 | 0.83 | PPARG (0.48) | PPARGALDH1A1SMN1; SMN2TSHRTP53 | |
| SCHEMBL8555355 | 0.83 | PPARG (0.46) | PPARGALDH1A1SMN1; SMN2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0869949-A1 | BENZOXAZINE ANTIMICROBIAL AGENTS | ORTHO PHARMACEUTICAL CORPORATION (US) | 1998-10-14 | — | — | EP | disclosed |
| WO-1997017333-A1 | BENZOXAZINE ANTIMICROBIAL AGENTS | ORTHO PHARMACEUTICAL CORPORATION (US) | 1997-05-15 | — | — | WO | disclosed |