Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
| ▸ | CASP1 | P29466 | 1/20 | 0.43 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.43 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | CDC25B | P30305 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | NPY1R | P25929 | 1/20 | 0.41 |
| ▸ | NPY2R | P49146 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6801265 | 0.85 | ALDH1A1 (0.62) | ALDH1A1MAPK1L3MBTL1TDP1CASP1 | |
| SCHEMBL28662041 | 0.80 | TDP1 (0.54) | ALDH1A1MAPK1L3MBTL1TDP1CYP4F2 | |
| SCHEMBL304176 | 0.79 | TDP1 (0.78) | ALDH1A1MAPK1L3MBTL1TDP1CASP1 | |
| SCHEMBL24405114 | 0.79 | ALDH1A1 (0.53) | ALDH1A1MAPK1L3MBTL1TDP1CASP1 | |
| SCHEMBL306178 | 0.79 | ALDH1A1 (0.53) | ALDH1A1MAPK1L3MBTL1TDP1CYP4F2 | |
| SCHEMBL24405103 | 0.79 | ALDH1A1 (0.53) | ALDH1A1MAPK1L3MBTL1TDP1CASP1 | |
| SCHEMBL27957232 | 0.79 | ALDH1A1 (0.53) | ALDH1A1MAPK1L3MBTL1TDP1CYP4F2 | |
| SCHEMBL6797888 | 0.78 | TSHR (0.46) | ALDH1A1TDP1CYP4F2CYP4A11LMNA | |
| Bicarbonate SCHEMBL7699565 | 0.77 | TDP1 (0.75) | ALDH1A1MAPK1L3MBTL1TDP1CASP1 | |
| SCHEMBL6800800 | 0.77 | PTGER1 (0.51) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0854863-A1 | ESTERS AND AMIDES AS PLA2 INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1998-07-29 | — | — | EP | disclosed |
| WO-1997003951-A1 | ESTERS AND AMIDES AS PLA2 INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1997-02-06 | — | — | WO | disclosed |