SCHEMBL8553536

SCHEMBL8553536

CCC(N)CN1CCCCC1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 2/20 0.46
KMT2A Q03164 2/20 0.46
ANPEP P15144 1/20 0.45
ERAP2 Q6P179 1/20 0.45
MAPT P10636 2/20 0.38
ATM Q13315 2/20 0.38
ABCB1 P08183 1/20 0.36
ALDH1A1 P00352 3/20 0.36
HPGD P15428 1/20 0.36
CYP2D6 P10635 4/20 0.36
POLB P06746 2/20 0.36
HSD17B10 Q99714 1/20 0.35
CYP2C19 P33261 1/20 0.35
KDM4E B2RXH2 1/20 0.35
HRH3 Q9Y5N1 2/20 0.34
CHRM2 P08172 1/20 0.34
ADRA2B P18089 1/20 0.34
ADRA2C P18825 1/20 0.34
CHRM3 P20309 1/20 0.34
DRD3 P35462 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28301902 1.00 MEN1 (0.46) MEN1KMT2AANPEPERAP2MAPT
SCHEMBL31391687 0.98 KMT2A (0.42) MEN1KMT2AANPEPERAP2MAPT
SCHEMBL1045080 0.87 PIK3CD (0.32) MEN1KMT2AANPEPERAP2ALDH1A1
SCHEMBL1674470 0.85 MEN1 (0.55) MEN1KMT2AANPEPERAP2MAPT
SCHEMBL990332 0.79 KDM4E (0.41) MEN1KMT2AMAPTALDH1A1POLB
SCHEMBL8227627 0.79 KDM4E (0.41) MEN1KMT2AMAPTALDH1A1POLB
SCHEMBL2914563 0.79 ANPEP (0.39) MEN1KMT2AANPEPERAP2MAPT
SCHEMBL991697 0.77 SMN1; SMN2 (0.44) ANPEPERAP2POLBCHRM2CHRM3
SCHEMBL171329 0.77 MEN1 (0.43) MEN1KMT2AANPEPERAP2MAPT
SCHEMBL3954978 0.77 USP2 (0.50) MEN1KMT2AANPEPALDH1A1CYP2D6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3892596-A1 GLASS FIBER-REINFORCED RESIN MOLDED ARTICLE Nitto Boseki Co., Ltd. (JP) 2021-10-13 EP disclosed
CN-109790125-A TETRAHYDROISOQUINOLINE KAPPA OPIOID ANTAGONISTS 研究三角协会 2019-05-21 CN disclosed
EP-0883613-A1 SULFONAMIDE DERIVATIVES AS 5HT7 RECEPTOR ANTAGONISTS SMITHKLINE BEECHAM PLC (GB) 1998-12-16 EP disclosed
WO-1997029097-A1 SULFONAMIDE DERIVATIVES AS 5HT7 RECEPTOR ANTAGONISTS SMITHKLINE BEECHAM PLC (GB) 1997-08-14 WO disclosed
US-4187226-A 1-(ALKOXYALKYLSULFONYLPHENYL/-3-PHENYLPYRAZOLINES, OPTICAL BRIGHTENERS BASF AKTIENGESELLSCHAFT (DE) 1980-02-05 US disclosed
US-4183851-A OPTICAL BRIGHTENERS BASF AKTIENGESELLSCHAFT (DE) 1980-01-15 US disclosed
US-4164500-A OPTICAL BRIGHTENERS BASF AKTIENGESELLSCHAFT (DE) 1979-08-14 US disclosed
US-4129563-A OPTICAL BRIGHTENERS BASF AKTIENGESELLSCHAFT (DE) 1978-12-12 US disclosed
US-4075211-A FLUORESCENT DYES FOR SYNTHETIC FIBERS BASF AKTIENGESELLSCHAFT (DT) 1978-02-21 US disclosed