SCHEMBL1674470

SCHEMBL1674470

NC(CN1CCCCC1)CN1CCCCC1

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.55
KMT2A Q03164 1/20 0.55
ANPEP P15144 1/20 0.52
ERAP2 Q6P179 1/20 0.52
MAPT P10636 2/20 0.44
ATM Q13315 2/20 0.44
HSD17B10 Q99714 1/20 0.40
HRH3 Q9Y5N1 2/20 0.39
ALDH1A1 P00352 2/20 0.36
HPGD P15428 1/20 0.36
L3MBTL1 Q9Y468 1/20 0.36
CYP2D6 P10635 2/20 0.35
CYP2C19 P33261 1/20 0.35
POLB P06746 2/20 0.35
KDM4E B2RXH2 1/20 0.35
LMNA P02545 2/20 0.35
CHRM5 P08912 1/20 0.35
ADRA2C P18825 1/20 0.35
TSHR P16473 1/20 0.33
HIF1A Q16665 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8553536 0.85 MEN1 (0.46) MEN1KMT2AANPEPERAP2MAPT
SCHEMBL14440763 0.85 MAPT (0.54) MEN1KMT2AANPEPERAP2MAPT
SCHEMBL8130430 0.82 MEN1 (0.55) MEN1KMT2AANPEPERAP2MAPT
SCHEMBL31391687 0.81 KMT2A (0.42) MEN1KMT2AANPEPERAP2MAPT
SCHEMBL171329 0.81 MEN1 (0.43) MEN1KMT2AANPEPERAP2MAPT
SCHEMBL4209395 0.79
SCHEMBL11590989 0.78 MEN1 (0.64) MEN1KMT2AANPEPERAP2MAPT
SCHEMBL358919 0.78 MEN1 (0.50) MEN1KMT2AANPEPERAP2MAPT
SCHEMBL6783279 0.78 MEN1 (0.50) MEN1KMT2AANPEPERAP2MAPT
SCHEMBL18205131 0.78 MEN1 (0.50) MEN1KMT2AANPEPERAP2MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 35 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2332998-B1 Solvent free aqueous polyurethane dispersions and methods of making and using the same VERSUM MAT US LLC (US) 2018-09-26 EP disclosed
US-9617453-B2 Solvent free aqueous polyurethane dispersions and methods of making and using the same AIR PRODUCTS AND CHEMICALS, INC. (US) 2017-04-11 US disclosed
EP-2308908-B1 Aqueous dispersion of a heat hardened polyurethane composition JANSEN BERNHARD (DE) 2014-06-25 EP disclosed
US-20110306724-A1 Solvent Free Aqueous Polyurethane Dispersions and Methods of Making and Using the Same AIR PRODUCTS AND CHEMICALS, INC. (US) 2011-12-15 US disclosed
EP-2332998-A1 Solvent free aqueous polyurethane dispersions and methods of making and using the same Air Products and Chemicals, Inc. (US) 2011-06-15 EP disclosed
EP-2308908-A1 Aqueous dispersion of a heat hardened polyurethane composition Jansen, Bernhard (DE) 2011-04-13 EP disclosed
US-20020055602-A1 Aromatic polyisocyanates blocked by pyrazole or pyrazole derivatives and the preparation and use thereof BAYER AKTIENGESELLSCHAFT (DE) 2002-05-09 US disclosed
EP-1184400-A1 Aromatic polyisocyanates blocked with pyrazole or pyrazole derivatives, process for their preparation and their use BAYER AG (DE) 2002-03-06 EP disclosed
US-5693737-A POLYETHERURETHANES FOR PREPARING CREASE-RESISTANT TEXTILES BAYER AKTIENGESELLSCHAFT (DE) 1997-12-02 US disclosed
US-5607482-A BLOCKED POLYISOCYANATE BAYER AKTIENGESELLSCHAFT (DE) 1997-03-04 US disclosed
US-4305858-A Process for the preparation of stable ionic dispersions of polyisocyanate-polyaddition products in hydroxyl containing compounds BAYER AKTIENGESELLSCHAFT (DE) 1981-12-15 US disclosed
US-4213898-A FOR POLYACRYLONITRILE SANDOZ LTD. (CH) 1980-07-22 US disclosed
US-4184990-A Process for the preparation of stable dispersions of polyisocyanate-polyaddition products in a hydroxyl containing compound as dispersing agent BAYER AKTIENGESELLSCHAFT (DE) 1980-01-22 US disclosed
US-4147680-A Production of polyurethane resins using as active hydrogen material a stable dispersion of ionic polyisocyanate-polyaddition products in hydroxyl containing compounds as a dispersing agent BAYER AKTIENGESELLSCHAFT (DE) 1979-04-03 US disclosed
US-4142030-A POLYURETHANE-SILICATE BAYER AKTIENGESELLSCHAFT (DE) 1979-02-27 US disclosed
US-4092275-A Polyurethane resins prepared from active hydrogen containing material which is a dispersion of polyisocyanate-polyaddition products in hydroxyl containing compounds as dispersing agents BAYER AKTIENGESELLSCHAFT (DT) 1978-05-30 US disclosed
US-4042536-A POLYISOCYANATE, SILICIC ACID, XEROGEL BAYER AKTIENGESELLSCHAFT (DT) 1977-08-16 US disclosed
US-4032532-A AZO DYES SANDOZ LTD. (CH) 1977-06-28 US disclosed
US-3998803-A TEXTILES FIDELITY UNION TRUST COMPANY, EXECUTIVE TRUSTEE UNDER THE SANDOZ TRUST (US) 1976-12-21 US disclosed
US-3970601-A COATINGS BAYER AKTIENGESELLSCHAFT (DT) 1976-07-20 US disclosed