Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 1/20 | 0.35 |
| ▸ | GABRA2 | P47869 | 3/20 | 0.35 |
| ▸ | GABRB2 | P47870 | 3/20 | 0.35 |
| ▸ | GABRP | O00591 | 2/20 | 0.35 |
| ▸ | GABRD | O14764 | 2/20 | 0.35 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.35 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.35 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.35 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.35 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.35 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.35 |
| ▸ | GABRA4 | P48169 | 2/20 | 0.35 |
| ▸ | GABRE | P78334 | 2/20 | 0.35 |
| ▸ | GABRA6 | Q16445 | 2/20 | 0.35 |
| ▸ | GABRG1 | Q8N1C3 | 2/20 | 0.35 |
| ▸ | GABRG3 | Q99928 | 2/20 | 0.35 |
| ▸ | GABRQ | Q9UN88 | 2/20 | 0.35 |
| ▸ | IKBKB | O14920 | 1/20 | 0.32 |
| ▸ | TNF | P01375 | 1/20 | 0.31 |
| ▸ | IL1B | P01584 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8556916 | 0.83 | IKBKB (0.37) | NOTUMGABRA2GABRB2GABRPGABRD | |
| SCHEMBL8399498 | 0.80 | GABRP (0.39) | NOTUMGABRA2GABRB2GABRPGABRD | |
| SCHEMBL8552378 | 0.78 | GABRP (0.38) | NOTUMGABRA2GABRB2GABRPGABRD | |
| SCHEMBL8553445 | 0.77 | — | — | |
| SCHEMBL8556532 | 0.76 | NOTUM (0.32) | NOTUMALDH1A1 | |
| SCHEMBL7254061 | 0.73 | IKBKB (0.39) | NOTUMGABRA2GABRB2GABRPGABRD | |
| SCHEMBL18424213 | 0.72 | GLP1R (0.36) | NOTUMGABRA2GABRB2GABRPGABRD | |
| SCHEMBL22366856 | 0.71 | GABRB3 (0.44) | NOTUMGABRA2GABRB2GABRPGABRD | |
| SCHEMBL8557118 | 0.69 | GABRB3 (0.41) | NOTUMGABRA2GABRB2GABRPGABRD | |
| SCHEMBL8555407 | 0.68 | GABRB3 (0.36) | NOTUMGABRA2GABRB2GABRPGABRD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0871617-A1 | PARASITICIDAL COMPOUNDS | PFIZER INC. (US) | 1998-10-21 | — | — | EP | disclosed |
| WO-1997007102-A1 | PARASITICIDAL COMPOUNDS | PFIZER INC (US) | 1997-02-27 | — | — | WO | disclosed |