Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.52 |
| ▸ | AVPR1A | P37288 | 2/20 | 0.51 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12964441 | 0.91 | SIGMAR1 (0.52) | SIGMAR1AVPR1AOPRD1 | |
| SCHEMBL12964404 | 0.85 | SIGMAR1 (0.48) | SIGMAR1AVPR1A | |
| SCHEMBL12964401 | 0.85 | SIGMAR1 (0.48) | SIGMAR1AVPR1A | |
| SCHEMBL14112077 | 0.85 | SIGMAR1 (0.47) | SIGMAR1AVPR1AOPRD1 | |
| SCHEMBL8557116 | 0.84 | SIGMAR1 (0.52) | SIGMAR1AVPR1A | |
| SCHEMBL6919513 | 0.83 | SIGMAR1 (0.57) | SIGMAR1OPRD1 | |
| SCHEMBL19121681 | 0.81 | SIGMAR1 (0.59) | SIGMAR1 | |
| SCHEMBL8554713 | 0.79 | SIGMAR1 (0.48) | SIGMAR1AVPR1A | |
| SCHEMBL9615977 | 0.79 | SIGMAR1 (0.54) | SIGMAR1AVPR1AOPRD1 | |
| SCHEMBL24507144 | 0.79 | SIGMAR1 (0.59) | SIGMAR1AVPR1AOPRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0649407-B1 | DIMERIC PIPERIDINE, TETRAHYDROPYRIDINE AND PIPERAZINE DERIVATIVES | LUNDBECK & CO AS H (DK) | 1998-08-05 | — | — | EP | claimed |
| EP-0649407-B1 | DIMERIC PIPERIDINE, TETRAHYDROPYRIDINE AND PIPERAZINE DERIVATIVES | LUNDBECK & CO AS H (DK) | 1998-08-05 | — | — | EP | disclosed |